Results 31 to 40 of about 495,024 (299)
Glycolipid-dependent and lectin-driven transcytosis in mouse enterocytes
Communications Biology, 2021 Ivashenka et al. report that galectin-3 (Gal3) binding to lactotransferrin drives its transcytosis in enterocytes. Such trafficking is Gal3- and glycosphingolipid-dependent, and Gal3 is found in clathrin-independent carriers.
Alena Ivashenka +13 more
doaj +1 more source
MAP4K4 regulates forces at cell–cell and cell–matrix adhesions to promote collective cell migration
Life Science Alliance, 2023 Using A431 carcinoma cells, the study shows that MAP4K4 coordinates cluster migration by regulating forces and stability of focal adhesions and adherens junctions, promoting cytoskeleton rearrangements. Collective cell migration is not only important for
Lara Elis Alberici Delsin +8 more
doaj +1 more source
Trafficking and cell migration [PDF]
Traffic, 2009 The migration of single cells and epithelial sheets is of great importance for gastrulation and organ formation in developing embryos and, if misregulated, can have dire consequences e.g. during cancer metastasis. A keystone of cell migration is the regulation of adhesive contacts, which are dynamically assembled and disassembled via endocytosis. Here,
Ulrich, F., Heisenberg, C.
openaire +3 more sources
Pathologies of Security Governance: Efforts Against Human Trafficking in Europe [PDF]
, 2007 The trafficking of women and girls for the purpose of sexual exploitation has reportedly been booming in Europe since the 1990s. Governments, international organizations, and private actors have addressed the causes and consequences of sex trafficking in
Friesendorf, Cornelius
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
iScience, 2023 Summary: Chemotaxis drives diverse migrations important for development and involved in diseases, including cancer progression. Using border cells in the Drosophila egg chamber as a model for collective cell migration, we characterized the role of ...
Alison Boutet +2 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Human trafficking & temporary guestworker visas
, 2023 This flier contains information about human trafficking and temporary guestworker ...
South Carolina Human Trafficking Task Force
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Social SciencesBackground: Individuals who are victimized and exploited by the heinous crimes of human trafficking (HT) access healthcare during their exploitation, yet gaps in education on HT content exist in prelicensure nursing programs.
Debra McWilliams +2 more
doaj +1 more source