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Intracellular trafficking [PDF]
Studies in C. elegans have begun to reveal new components and new mechanisms associated with intracellular membrane traffic in a variety of cell types. The worm benefits from many of the advantages of yeast as a genetically tractable organism for these kinds of studies while offering the unique opportunity to probe how these pathways have been extended
Barth D, Grant, Miyuki, Sato
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This first-person narrative describes some of the barriers to caring well for patients at the intersection of human trafficking and substance use disorder. I canvass some of the ethical considerations regarding these patients' autonomy and call for establishing and using evidence-based practice to manage these complex scenarios.
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Attempts to prevent trafficking are increasing the problems of those who migrate voluntarily Trafficking in women and children is now recognised as a global public health issue as well as a violation of human rights. The UN Protocol to Prevent, Suppress, and Punish Trafficking in Persons, especially Women and Children states that trafficking involves
Busza, Joanna +2 more
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Maritime delimitation, which ensures the jurisdiction exertion and effective use of maritime spaces of coastal States, never involves minimal efforts.
Quyen Mai Nguyen, Linh Thao Nguyen
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HIV-1 Gag Blocks Selenite-Induced Stress Granule Assembly by Altering the mRNA Cap-Binding Complex
Stress granules (SGs) are dynamic accumulations of stalled preinitiation complexes and translational machinery that assemble under stressful conditions.
Alessandro Cinti +3 more
doaj +1 more source
Multiple Domains in the Kv7.3 C-Terminus Can Regulate Localization to the Axon Initial Segment
The voltage-gated Kv7.2/Kv7.3 potassium channel is a critical regulator of neuronal excitability. It is strategically positioned at the axon initial segment (AIS) of neurons, where it effectively inhibits repetitive action potential firing.
Louise Leth Hefting +4 more
doaj +1 more source
HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases
HIV-1 co-opts several host machinery to generate a permissive environment for viral replication and transmission. In this work we reveal how HIV-1 impacts the host translation and intracellular vesicular trafficking machineries for protein synthesis and ...
Alessandro Cinti +8 more
doaj +1 more source
The Public Health Impact of Coronavirus Disease on Human Trafficking
The global pandemic of severe acute respiratory syndrome coronavirus 2 exacerbates major risk factors for global human trafficking. Social isolation of families and severe economic distress amplify the risk of interpersonal violence, unemployment and ...
Jordan Greenbaum +5 more
doaj +1 more source
Human trafficking and internet safety
This flier contains information on human trafficking and internet ...
South Carolina Human Trafficking Task Force
core +1 more source
Regulation of Viral Restriction by Post-Translational Modifications
Intrinsic immunity is orchestrated by a wide range of host cellular proteins called restriction factors. They have the capacity to interfere with viral replication, and most of them are tightly regulated by interferons (IFNs).
Célia Chamontin +4 more
doaj +1 more source

