Results 11 to 20 of about 318,672 (261)
Intracellular trafficking [PDF]
WormBook, 2006 Studies in C. elegans have begun to reveal new components and new mechanisms associated with intracellular membrane traffic in a variety of cell types. The worm benefits from many of the advantages of yeast as a genetically tractable organism for these kinds of studies while offering the unique opportunity to probe how these pathways have been extended
Barth D, Grant, Miyuki, Sato
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AMA Journal of Ethics, 2018 This first-person narrative describes some of the barriers to caring well for patients at the intersection of human trafficking and substance use disorder. I canvass some of the ethical considerations regarding these patients' autonomy and call for establishing and using evidence-based practice to manage these complex scenarios.
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BMJ, 2004 Attempts to prevent trafficking are increasing the problems of those who migrate voluntarily Trafficking in women and children is now recognised as a global public health issue as well as a violation of human rights. The UN Protocol to Prevent, Suppress, and Punish Trafficking in Persons, especially Women and Children states that trafficking involves
Busza, Joanna +2 more
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Frontiers in Conservation Science, 2021 Wildlife trafficking is a complex conservation issue that threatens thousands of species around the world and, in turn, negatively affects biodiversity and human well-being.
Christine Browne +7 more
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HIV-1 Gag Blocks Selenite-Induced Stress Granule Assembly by Altering the mRNA Cap-Binding Complex
mBio, 2016 Stress granules (SGs) are dynamic accumulations of stalled preinitiation complexes and translational machinery that assemble under stressful conditions.
Alessandro Cinti +3 more
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The Public Health Impact of Coronavirus Disease on Human Trafficking
Frontiers in Public Health, 2020 The global pandemic of severe acute respiratory syndrome coronavirus 2 exacerbates major risk factors for global human trafficking. Social isolation of families and severe economic distress amplify the risk of interpersonal violence, unemployment and ...
Jordan Greenbaum +5 more
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Multiple Domains in the Kv7.3 C-Terminus Can Regulate Localization to the Axon Initial Segment
Frontiers in Cellular Neuroscience, 2020 The voltage-gated Kv7.2/Kv7.3 potassium channel is a critical regulator of neuronal excitability. It is strategically positioned at the axon initial segment (AIS) of neurons, where it effectively inhibits repetitive action potential firing.
Louise Leth Hefting +4 more
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HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases
Scientific Reports, 2017 HIV-1 co-opts several host machinery to generate a permissive environment for viral replication and transmission. In this work we reveal how HIV-1 impacts the host translation and intracellular vesicular trafficking machineries for protein synthesis and ...
Alessandro Cinti +8 more
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Complete structure of the bacterial flagellar hook reveals extensive set of stabilizing interactions
Nature Communications, 2016 The bacterial flagellar hook is made up of many copies of the protein FlgE. Here, the authors report the full structure of the hook from Campylobacter jejuni and show that its overall structure is different from that of the previously published filament.
Hideyuki Matsunami +4 more
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Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway
Viruses, 2016 The mammalian target of rapamycin (mTOR) is a central regulator of gene expression, translation and various metabolic processes. Multiple extracellular (growth factors) and intracellular (energy status) molecular signals as well as a variety of stressors
Valerie Le Sage +3 more
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