Results 201 to 210 of about 157,979 (250)
Advanced Science, EarlyView.A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang +15 more
wiley +1 more source
Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration
Advanced Science, EarlyView.This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya +10 more
wiley +1 more source
Advanced Science, EarlyView.Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen +17 more
wiley +1 more source
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2021
Autophagy is a major intracellular degradation/recycling system that ubiquitously exists in eukaryotic cells. Autophagy contributes to the turnover of cellular components through engulfing portions of the cytoplasm or organelles and delivering them to the lysosomes/vacuole to be degraded.
Jingjing, Ye, Ming, Zheng
openaire +2 more sources
Autophagy is a major intracellular degradation/recycling system that ubiquitously exists in eukaryotic cells. Autophagy contributes to the turnover of cellular components through engulfing portions of the cytoplasm or organelles and delivering them to the lysosomes/vacuole to be degraded.
Jingjing, Ye, Ming, Zheng
openaire +2 more sources
2013
The continuous production of T lymphocytes requires that hematopoietic progenitors developing in the bone marrow migrate to the thymus. Rare progenitors egress from the bone marrow into the circulation, then traffic via the blood to the thymus. It is now evident that thymic settling is tightly regulated by selectin ligands, chemokine receptors, and ...
Shirley L, Zhang, Avinash, Bhandoola
openaire +2 more sources
The continuous production of T lymphocytes requires that hematopoietic progenitors developing in the bone marrow migrate to the thymus. Rare progenitors egress from the bone marrow into the circulation, then traffic via the blood to the thymus. It is now evident that thymic settling is tightly regulated by selectin ligands, chemokine receptors, and ...
Shirley L, Zhang, Avinash, Bhandoola
openaire +2 more sources
Combatting Sex Trafficking Through the Prosecution of Traffickers
2017This chapter discusses the use of criminal prosecution as a means to combat human trafficking. It analyses the common attributes of traffickers and facets of sex trafficking that inhibit investigation and prosecution of sex trafficking. Trafficking of human beings occurs because it is profitable for traffickers.
Michael J. Frank, G. Zachary Terwilliger
openaire +1 more source
Trafficking Without Traffickers
The Trafficking Victims Protection Act (TVPA) does not recognize forced labor in circumstances where work is structurally, rather than interpersonally, coerced. By locating the power to impose coercion exclusively in individual actors, the law 1) denies relief to survivors of structurally coerced trafficking and 2) shields coercive laws from blame.openaire +2 more sources