Results 21 to 30 of about 904,971 (330)
HIV-1 Gag Blocks Selenite-Induced Stress Granule Assembly by Altering the mRNA Cap-Binding Complex
mBio, 2016 Stress granules (SGs) are dynamic accumulations of stalled preinitiation complexes and translational machinery that assemble under stressful conditions.
Alessandro Cinti +3 more
doaj +1 more source
Frontiers in Conservation Science, 2021 Wildlife trafficking is a complex conservation issue that threatens thousands of species around the world and, in turn, negatively affects biodiversity and human well-being.
Christine Browne +7 more
doaj +1 more source
Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19
Nature reviews. Immunology, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes underlying the versatile clinical manifestations of COVID-19 is incomplete without ...
R. Alon +7 more
semanticscholar +1 more source
European Journal of Immunology, 2020 Unlike hematological malignancies, solid tumors have proved to be less susceptible to chimeric antigen receptor (CAR)‐T cell therapy, which is partially caused by reduced accumulation of therapeutic T cells in tumor site.
Guangna Liu +8 more
semanticscholar +1 more source
HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases
Scientific Reports, 2017 HIV-1 co-opts several host machinery to generate a permissive environment for viral replication and transmission. In this work we reveal how HIV-1 impacts the host translation and intracellular vesicular trafficking machineries for protein synthesis and ...
Alessandro Cinti +8 more
doaj +1 more source
The Public Health Impact of Coronavirus Disease on Human Trafficking
Frontiers in Public Health, 2020 The global pandemic of severe acute respiratory syndrome coronavirus 2 exacerbates major risk factors for global human trafficking. Social isolation of families and severe economic distress amplify the risk of interpersonal violence, unemployment and ...
Jordan Greenbaum +5 more
doaj +1 more source
Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
Nanoscale Research Letters, 2018 Nanoparticle science is rapidly changing the landscape of various scientific fields and defining new technological platforms. This is perhaps even more evident in the field of nanomedicine whereby nanoparticles have been used as a tool for the treatment ...
Parisa Foroozandeh, A. Aziz
semanticscholar +1 more source
Multiple Domains in the Kv7.3 C-Terminus Can Regulate Localization to the Axon Initial Segment
Frontiers in Cellular Neuroscience, 2020 The voltage-gated Kv7.2/Kv7.3 potassium channel is a critical regulator of neuronal excitability. It is strategically positioned at the axon initial segment (AIS) of neurons, where it effectively inhibits repetitive action potential firing.
Louise Leth Hefting +4 more
doaj +1 more source
Complete structure of the bacterial flagellar hook reveals extensive set of stabilizing interactions
Nature Communications, 2016 The bacterial flagellar hook is made up of many copies of the protein FlgE. Here, the authors report the full structure of the hook from Campylobacter jejuni and show that its overall structure is different from that of the previously published filament.
Hideyuki Matsunami +4 more
doaj +1 more source
Anti-Trafficking Review, 2015 The Trafficking Protocol[1] has shaped and advanced a global movement against human trafficking; notably through establishing a global definition and creating criminal justice remedies befitting an international crime.[2] Borne out of and including the ...
Kathryn Baer
doaj +1 more source