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Complete structure of the bacterial flagellar hook reveals extensive set of stabilizing interactions
The bacterial flagellar hook is made up of many copies of the protein FlgE. Here, the authors report the full structure of the hook from Campylobacter jejuni and show that its overall structure is different from that of the previously published filament.
Hideyuki Matsunami +4 more
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The Trafficking Protocol[1] has shaped and advanced a global movement against human trafficking; notably through establishing a global definition and creating criminal justice remedies befitting an international crime.[2] Borne out of and including the ...
Kathryn Baer
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When politicians, responding to public campaigns focused on human trafficking, make bold and over-emotive statements, invoking William Wilberforce and the pressing need to lead the global fight against slavery, the Trafficking Protocol,[1] proves its ...
Caroline Parkes
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Regulation of Viral Restriction by Post-Translational Modifications
Intrinsic immunity is orchestrated by a wide range of host cellular proteins called restriction factors. They have the capacity to interfere with viral replication, and most of them are tightly regulated by interferons (IFNs).
Célia Chamontin +4 more
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Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway
The mammalian target of rapamycin (mTOR) is a central regulator of gene expression, translation and various metabolic processes. Multiple extracellular (growth factors) and intracellular (energy status) molecular signals as well as a variety of stressors
Valerie Le Sage +3 more
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West Nile Virus Restriction in Mosquito and Human Cells: A Virus under Confinement
West Nile virus (WNV) is an emerging neurotropic flavivirus that naturally circulates between mosquitoes and birds. However, WNV has a broad host range and can be transmitted from mosquitoes to several mammalian species, including humans, through ...
Marie-France Martin, Sébastien Nisole
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Background Mammalian cells harbour RNA quality control and degradative machineries such as nonsense-mediated mRNA decay that target cellular mRNAs for clearance from the cell to avoid aberrant gene expression.
Shringar Rao +5 more
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Conceptualizing Task Force Sustainability
In the anti-human trafficking movement, multi-disciplinary teams have emerged as a best practice for collaborating and coordinating efforts in combating human trafficking.
Jennifer Paul Ray
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Victim or whore: The similarities and differences between victim’s experiences of domestic violence and sex trafficking [PDF]
This research review addresses the similarities and differences between domestic violence and sex trafficking victimization. While there is evidence that domestic violence and sex trafficking often cooccur, there is a large disparity in the ...
Dahlstedt, Jaime +3 more
core +1 more source
Background In a macro-molecular complex, any minor change may prove detrimental. For a supra-molecular nano-machine like the bacterial flagellum, which consists of several distinct parts with specific characteristics, stability is important.
Clive S. Barker +4 more
doaj +1 more source

