Results 71 to 80 of about 27,212 (306)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Reduced dimension modeling of leading edge turbulent interaction noise [PDF]

open access: yes, 2014
A computational aeroacoustics approach is used to model the effects of real airfoil geometry on leading edge turbulent interaction noise for symmetric airfoils at zero angle of attack.
Zhang, Xin   +7 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Subcomponent testing: Trailing edge

open access: yes, 2023
Sub-component testing of a trailing edge segments which were cutout from a rotor blade of a wind turbine has been demonstrated to successfully work under static compression, e.g., buckling. However, the actual and representative loading a blade is subjected to in field is a cyclic tension-compression or tension-tension load depending on the position ...
Rosemeier, Malo   +3 more
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Aerodynamics and aeroacoustics of flap side-edges [PDF]

open access: yes, 2008
An experimental and computational investigation was carried out to determine the aerodynamics and aeroacoustics of a flap side-edge. A porous side-edge treatment was applied to the flap side-edge in an attempt to reduce airframe noise. Measurements taken
Angland, David
core  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Computation of Trailing Edge Noise with a Discontinuous Galerkin Method

open access: yes, 2008
Trailing edge noise of a semi-infinite, thin, flat plate situated in low Mach number flow is computed in two spatial dimensions. The Acoustic Pertur- bation Equations (APE), which are employed as governing equations, are discretized via a ...
Bauer, Marcus
core  

Home - About - Disclaimer - Privacy