Results 61 to 70 of about 27,212 (306)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Examination of three candidate technologies for high-lift devices on an aircraft wing [PDF]
, 2005 A research programme was initiated to examine three candidate high-lift technologies, which would, if implemented, simplify the mechanical complexity of the multiple component trailing-edge devices traditionally employed on civil transport aircraft ...
Knepper, Angela Marie
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Design methodology for wing trailing edge device mechanisms [PDF]
, 2007 Over the last few decades the design of high lift devices has become a very important part of the total aircraft design process. Reviews of the design process are performed on a regular basis, with the intent to improve and optimize the design process.
Martins Pires, Rui Miguel
core
Advances in Mechanical Engineering, 2013 The turbine blade works at high thermal loads, especially the trailing edge of the blade due to the hot gas leakage flow. Pin-fins are well recognized as a kind of effective device to augment the convective heat transfer and effectively cool the trailing
Qitao Zhou +4 more
doaj +1 more source
Advanced Engineering Research, 2016 The work objective is to evaluate how the geometric transformations of the trailing edge of some airfoils affect the aerodynamic characteristics. Such transformations as the trailing edge thickening and rounding are considered.
Konstantin I. Mescheryakov +1 more
doaj +1 more source
Spanning trails containing given edges
Discrete Mathematics, 2006 Let \(r\geq 0\) be an integer. A graph \(G\) is called \(r\)-Eulerian-connected if for any \(X\subseteq E(G)\) with \(| X| \leq r\) and for any two vertices \(u,v\in V(G)\) (including the case \(u=v\)), the graph \(G\) has a spanning \((u,v)\)-trail containing all edges of \(X\), and \(G\) is called \(r\)-edge-Eulerian-connected if for any \(X\subseteq
Luo, Weiqi +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source