Results 51 to 60 of about 27,212 (306)

Multi-Size-Mesh, Multi-Time-Step Algorithm for Noise Computation on Curvilinear Meshes [PDF]

, 2013
Aeroacoustic problems are often multi-scale and a zonal refinement technique is thus desirable to reduce computational effort while preserving low dissipation and low dispersion errors from the numerical scheme.
CORRE, Christophe, LE GARREC, Thomas, GLOERFELT, Xavier, Corre, Christophe Eric   +3 more
core   +1 more source

Numerical and Experimental Investigations of Axial Flow Fan with Bionic Forked Trailing Edge

Machines, 2023
To improve the performance of the aerodynamic properties and reduce the aerodynamic noise of an axial flow fan in the outdoor unit of an air conditioner, this study proposed a bionic forked trailing-edge structure inspired by the forked fish caudal fin ...
Zhong Liang, Jun Wang, Wei Wang, Boyan Jiang, Yanyan Ding, Wanxiang Qin   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Broadband Noise Reduction of a Two-Stage Fan with Wavy Trailing-Edge Blades

Aerospace
In this paper, a numerical investigation is performed to study the broadband noise of a fan stage with wavy trailing-edge blades. A study of the wavelength and ratio of amplitude to wavelength (H/L) is conducted to better understand the noise reduction ...
Ruibiao Gao, Weijie Chen, Hang Tong, Jianxin Lian, Weiyang Qiao   +4 more
doaj   +1 more source

A Study of the Dependence of the Mach Stem Height on the Trailing Edge Height

Fluids, 2021
The Mach stem height is an important parameter in the Mach reflection of steady supersonic flow. Various experimental, numerical, and theoretical works have been conducted to study this parameter in the past. However, much of the established work focuses
Chen-Yuan Bai, Zi-Niu Wu
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Influence of Gurney Flap and Leading-Edge/Trailing-Edge Flaps on the Stall Characteristics and Aeroacoustic Performance of Airfoils

Fluids
In aerospace, flow control techniques have improved the separation flow characteristics around airfoils by various means. In this paper, the delayed detached eddy simulation (DDES) technique is used to simulate the detailed flow field around the NACA0021
Zelin Liu, Kaidi Li, Xiaojing Sun
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Prediction of contra-rotating open rotor broadband noise in isolated and installed configurations

, 2014
Broadband noise is a significant part of the noise emitted by contra-rotating open rotors. Several noise sources can contribute to the total broadband sound field, with the most dominant ones probably being trailing edge noise, rotor-wake interaction ...
Zhang, Xin, Chen, Xiaoxian, Parry, Anthony B., Thomas Node-Langlois, Caruelle, Bastien, James R. Gill, Xin Zhang, Fabien Wlassow, Yann Colin, Bastien Caruelle, Anthony B. Parry, Languille, Vianney, Node-Langlois, Thomas, Vianney Languille, Xiaoxian Chen, Gill, James R., Colin, Yann, Wlassow, Fabien   +17 more
core   +1 more source