Results 101 to 110 of about 962,136 (301)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Materials & DesignSimultaneous enhancement of impact resistance and heat dissipation remains a critical bottleneck in the design of advanced metastructures. Drawing on inspiration from arch bridges, this work proposes a multifunctional sandwich metastructure.
Yanxi Zhao +4 more
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
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Two-Dimensional Porous Structure of V‑Doped NiO with Enhanced Electrochromic Properties
ACS Omega, 2022 Xuhe Zhan +4 more
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Hydrolysis behavior and mechanism of AlON powders
Materials & DesignAlON-C (∼25 μm) powders were prepared using the carbothermal reduction and nitridation (CRN) method. The powders were subsequently processed through milling to obtain AlON-M (∼1.6 μm) and AlON-F (∼456 nm).
Jianxin Xu +4 more
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French Gratitude Train on railroad tracks
, 1950 Photograph of the exterior of the French Gratitude Train parked on an unknown set of railroad tracks in Ohio. On the exterior are crests from the different regions of France. In 1948 the United States sent a large shipment of food, fuel and clothing to
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
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To Train or Not to Train? [PDF]
Journal of Teacher Education for Sustainability, 2009 Nwachukwu Ololube +2 more
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
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, 1961 Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about a train colliding with a truck in Fort ...
WBAP-TV (Television station : Fort Worth, Tex.)
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