Results 51 to 60 of about 962,136 (301)

Method for evaluating the accuracy of state‐of‐charge (SOC)/state‐of‐health (SOH) estimation of BMSs

Energy Science & Engineering, 2023
The battery management system (BMS), which is widely adopted in various eco‐friendly automobiles that use batteries for propulsion, increases energy efficiency and extends the usable life by monitoring and optimally managing batteries.
Hyunsik Song, Donghyun Shin
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Enhanced Anti-Rollover Control for Commercial Vehicles Under Dynamic Lateral Interferences

Designs
Commercial vehicles frequently experience lateral interferences, such as crosswinds or side slopes, during extreme maneuvers like emergency steering and high-speed driving due to their high centroid.
Jin Rong, Tong Wu, Junnian Wang, Jing Peng, Xiaojun Yang, Yang Meng, Liang Chu   +6 more
doaj   +1 more source

An efficient method for train–track–substructure dynamic interaction analysis by implicit-explicit integration and multi-time-step solution

Railway Engineering Science, 2022
In this work, a method is put forward to obtain the dynamic solution efficiently and accurately for a large-scale train–track–substructure (TTS) system. It is called implicit-explicit integration and multi-time-step solution method (abbreviated as mI-nE ...
Lei Xu, Wanming Zhai, Shengyang Zhu, Weizheng Liu   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A Finite-Element Model of Seated Human Body Representing the Distribution of Static Pressures and Dynamic Forces over a Rigid Seat During Vertical Vibration for Sitting Postures with Various Thigh Contact

Applied Sciences
Overall sitting comfort is related to both static pressure distribution and dynamic human–seat interaction during vibration. This study proposes a simplified finite-element model of the seated human body that could potentially be used to assess overall ...
Weitan Yin, Shaoqing Liu, Jianying Liang, Chi Liu, Yi Qiu, Xu Zheng, Linfeng Sun, Shan Huang   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source