Results 101 to 110 of about 2,585,798 (346)

Modeling and optimization of urban rail transit scheduling with adaptive fruit fly optimization algorithm

Open Physics, 2019
Despite the rapid development of urban rail transit in China, there are still some problems in train operation, such as low efficiency and poor punctuality.
Li Jin, Xu Guangyin, Wang Zhengfeng, Wang Zhanwu   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Visualization of Event Graphs for Train Schedules

CoRR
Train timetables can be represented as event graphs, where correspond to a train passing through a location at a certain point in time. A visual representation of an event graph is important for many applications such as dispatching and (the development of) dispatching software. A common way to represent event graphs are time-space diagrams.
Hartleb, Johann, Schmidt, Marie, Wolf, Samuel, Wolff, Alexander   +3 more
openaire   +3 more sources

Integrated Design of Smart Train Scheduling, Use of Onboard Energy Storage, and Traction Power Management for Energy-Saving Urban Railway Operation

IEEJ Journal of Industry Applications, 2019
This paper presents an integrated design of train scheduling, use of onboard energy storage, and traction power management for urban railways. The proposed design aims to integrate the design of train operation and infrastructure to improve energy-saving
W. Kampeerawat, T. Koseki
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Railway track capacity: measuring and managing

, 2012
This thesis adopts a holistic approach towards railway track capacity to develop methodologies for different aspects of defining, measuring, analysing, improving and controlling track capacity utilisation. Chapter 1 presents an overview of the concept of
Khadem Sameni, M., Khadem Sameni, M
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Tabu search for ship routing and scheduling

, 2006
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 20/12/2006.This thesis examines exact and heuristic approaches to solve the Ship Routing and Scheduling Problem (SRSP). The method was developed to address
Al-Hamad, Khaled
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Train Schedule Adjustment Strategies for Train Dispatch

TELKOMNIKA Indonesian Journal of Electrical Engineering, 2013
Train schedule adjustment is the identity of key components of Train Dispatch System. Manually arranging the time table is a time-consuming and error-prone process. In this work, we mainly discuss three strategies of train schedule adjustment in train dispatch. First, we propose a new algorithm to calculate the maximum traffic capacity of freight-train
Huaqing Mao, Zhu Li
openaire   +1 more source