Results 81 to 90 of about 2,585,798 (346)

Joint Optimization Method for Preventive Maintenance and Train Scheduling of Subway Vehicles Based on a Spatiotemporal Network Graph

Applied Sciences
To address the challenges posed by the interdependence between subway vehicle scheduling and maintenance planning, which complicates joint optimization modeling and solution processes, this study proposes a spatiotemporal network-based joint optimization
Chuanzhen Liu, Zhongwei Xu, Meng Mei, Wenqing Li   +3 more
doaj   +1 more source

Changes in the carriage and traffic capacity along highly busy routes in case of traffic scheduling for permanently linked multiple trains

Вестник Научно-исследовательского института железнодорожного транспорта, 2019
The increase in transportation volume through the railroad network requires novel less capital-intensive methods for increasing the carriage capacity with respect to the busy routes that operate at traffic capacity levels of 0.8 and higher.
Evgeniy A. Sotnikov, Pavel S. Kholodnyak
doaj   +1 more source

Train Scheduling for Minimizing the Total Travel Time With a Skip-Stop Operation in Urban Rail Transit

IEEE Access, 2019
The skip-stop operating mode for urban rail transit systems defines three types of stations: A, B, and AB stations. In this strategy, all the trains stop at AB stations, and A (B) trains stop at only A (B) stations.
Anan Yang, Jianling Huang, Bo Wang, Yanyan Chen   +3 more
semanticscholar   +1 more source

Heuristic techniques for train scheduling

, 1997
Optimising a train schedule on a single line track is known to be NP-Hard with respect to\ud the number of conflicts in the schedule. This makes it difficult to determine optimum\ud solutions to real life problems in reasonable time and raises the need ...
Kozan, Erhan, Higgins, Andrew, Ferreira, Luis   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The course scheduling problem at Lufthansa Technical Training [PDF]

European Journal of Operational Research, 1998
Abstract Lufthansa Technical Training GmbH (LTT) performs training courses for Lufthansa Technik AG as well as for several other international airlines. Courses of about 670 different types are offered of which several hundred take place each year. The course scheduling problem faced by LTT is to construct a yearly schedule which maximizes the profit
Knut Haase, Jörg Latteier, Andreas Schirmer   +2 more
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Train scheduling with application to the UK rail network

, 2013
Nowadays, transforming the railway industry for better performance and making the best usage of the current capacity are the key issues in many countries.
Khosravi, Banafsheh
core  

Scheduling trains as a blocking parallel-machine job shop scheduling problem

, 2009
In this paper, the train scheduling problem is modelled as a blocking parallel-machine job shop scheduling (BPMJSS) problem. In the model, trains, single-track sections and multiple-track sections, respectively, are synonymous with jobs, single machines ...
Kozan, Erhan, Liu, Shi Qiang
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source