Results 131 to 140 of about 2,585,798 (346)

Development of the method for modeling the propagation of delays in non­cyclic train scheduling on the railroads with mixed traffic

, 2018
The main goal of present study is to develop a method for modeling delay propagation in non-cyclic train scheduling on a railroad network with mixed traffic.
Tatyana But’ko, A. Prokhorchenko, Tetiana Golovko, G. Prokhorchenko   +3 more
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Disruption management in passenger railway transportation.

This paper deals with disruption management in passengerrailway transportation. In the disruption management process, manyactors belonging to different organizations play a role.
Potthoff, D., Clausen, J., Nielsen, M.N., Kroon, L.G., Huisman, D., Maroti, G., Jespersen-Groth, J.   +6 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Concurrent Locomotive Assignment and Freight Train Scheduling

International Journal of Industrial Engineering and Production Research, 2016
The locomotive assignment and the freight train scheduling are important problems in railway transportation. Freight cars are coupled to form a freight rake. The freight rake becomes a train when a locomotive is coupled to it.
Masoud Yaghini, Faeze Ghofrani, Mohammad Karimi, Majedeh Esmi-Zadeh   +3 more
doaj  

Operations research in passenger railway transportation

In this paper, we give an overview of state-of-the-art OperationsResearch models and techniques used in passenger railwaytransportation. For each planning phase (strategic, tactical andoperational), we describe the planning problems arising there ...
Vromans, M.J.C.M., Kroon, L.G., Huisman, D., Lentink, R.M.   +3 more
core  

Mixed integer-linear formulations of cumulative scheduling constraints - A comparative study [PDF]

, 2007
This paper introduces two MILP models for the cumulative scheduling constraint and associated pre-processing filters. We compare standard solver performance for these models on three sets of problems and for two of them, where tasks have unitary resource
Aronsson, Martin, Kreuger, Per, Bohlin, Markus   +2 more
core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Cost Optimal Train Scheduling

, 2003
. For some real world railroad networks, we minimize certain operational cost of train schedules which allow different train types of diverse speed and cost. We use a mixed integer linear programming approach to model this train scheduling problem.
Uwe T. Zimmermann, Thomas Lindner
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source