Results 21 to 30 of about 1,457,117 (258)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Prevalence of hepatitis B infection among tricycle waste collectors, Greater Kumasi Ghana

open access: yesDiscover Public Health
Tricycle waste workers, who play a vital role in waste management, are exposed to various occupational hazards, including viral hepatitis B (HBV) infection.
Joseph Appiah   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

When looking at an immersive 360° hypervideo is close to direct experience: a pilot study on stress-related psychophysiological activation in simulations with paramedics

open access: yesEmpirical Research in Vocational Education and Training
Emergency contexts are emotionally demanding, particularly for trainees. This pilot study compared the psychophysiological activation of 23 paramedic students during two simulations: a direct simulation, in which they performed a simulated road rescue in
Rita Cosoli   +3 more
doaj   +1 more source

Talent retention strategies and employees’ behavioural outcomes: empirical evidence from hospitality industry

open access: yesBusiness: Theory and Practice, 2020
To enhance the extant literature of talent retention and proffering solution to the negative employees’ behavioural outcomes of high performers in hospitality industry, this study investigates the influence of talent retention strategies (training and ...
Folakemi Ohunakin   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Technological Pedagogical Content Knowledge of Pre-service Teachers in Ghana

open access: yesActa Educationis Generalis
Introduction: Technological Pedagogical Content Knowledge (TPACK) is a framework that integrates the domains of technology, pedagogy, and content knowledge to enhance teachers’ understanding of how they can effectively incorporate technology into their ...
Boateng Philip   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Hematological, biochemical, and histopathological changes in laboratory rats naturally infected with gastrointestinal parasites

open access: yesDiscover Animals
Background Gastrointestinal parasites can impact the health and research value of laboratory animals. Laboratory rats were examined to investigate physiological changes following natural infections with intestinal parasites.
Samuel Ayetibo Ofori   +5 more
doaj   +1 more source

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