Results 21 to 30 of about 477,994 (265)
On the Effect of Asymmetrical Trait Inheritance on Models of Trait Evolution [PDF]
Systematic Biology, 2019 Abstract Current phylogenetic comparative methods modeling quantitative trait evolution generally assume that, during speciation, phenotypes are inherited identically between the two daughter species. This, however, neglects the fact that species consist of a set of individuals, each bearing its own trait value.
Duchen, Pablo +4 more
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Frontiers in Cellular Neuroscience, 2017 Induced pluripotent stem cell (iPSC) technology is more and more used for the study of genetically complex human disease but is challenged by variability, sample size and polygenicity.
Stephanie D. Hoekstra +5 more
doaj +1 more source
Memory in trait macroevolution [PDF]
The American Naturalist, 2018 Abstract The history of a trait within a lineage may influence its future evolutionary trajectory, but macroevolutionary theory of this process is not well developed. For example, consider the simple binary trait of living in cave versus surface habitat.
Goldberg, Emma E., Foo, Jasmine
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Nature Communications, 2018 Educational attainment and schizophrenia have a negative phenotypic relationship but show positive genetic correlation. Here, the authors study genetic dependence between the two traits and find that multiple genes have pleiotropic effects on both ...
V. Bansal +12 more
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Frontiers in Ecology and Evolution, 2022 The traits of organisms provide critical information for understanding changes in biodiversity and ecosystem function at large scales. In recent years, trait databases of macroinvertebrates have been developed across continents.
Sicheng Ao +10 more
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Proceedings of the 2007 international conference on Dynamic languages: in conjunction with the 15th International Smalltalk Joint Conference 2007, 2007 Recently, traits have been proposed as a single inheritance backward compatible solution in which the composing entity has the control over the trait composition. Traits are fine-grained units used to compose classes, while avoiding many of the problems of multiple inheritance and mixin-based approaches.To evaluate the expressiveness of traits, some ...
Damien Cassou +2 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Functional mapping and annotation of genetic associations with FUMA
Nature Communications, 2017 Prioritizing genetic variants is a major challenge in genome-wide association studies. Here, the authors develop FUMA, a web-based bioinformatics tool that uses a combination of positional, eQTL and chromatin interaction mapping to prioritize likely ...
Kyoko Watanabe +3 more
doaj +1 more source