Results 41 to 50 of about 1,679,257 (365)

Item-level analyses reveal genetic heterogeneity in neuroticism

open access: yesNature Communications, 2018
Neuroticism can be assessed as a composite score of individual items. Here, Nagel et al. perform genetic association studies for 12 neuroticism items and the sum-score and demonstrate genetic heterogeneity at the item-level.
Mats Nagel   +4 more
doaj   +1 more source

Genetically-Informed Patient Selection for iPSC Studies of Complex Diseases May Aid in Reducing Cellular Heterogeneity

open access: yesFrontiers in Cellular Neuroscience, 2017
Induced pluripotent stem cell (iPSC) technology is more and more used for the study of genetically complex human disease but is challenged by variability, sample size and polygenicity.
Stephanie D. Hoekstra   +5 more
doaj   +1 more source

Transient LTRE analysis reveals the demographic and trait-mediated processes that buffer population growth. [PDF]

open access: yes, 2018
Temporal variation in environmental conditions affects population growth directly via its impact on vital rates, and indirectly through induced variation in demographic structure and phenotypic trait distributions. We currently know very little about how
Armitage, Kenneth B   +3 more
core   +2 more sources

Trait-trait dynamic interaction: 2D-trait eQTL mapping for genetic variation study [PDF]

open access: yesBMC Genomics, 2008
AbstractBackgroundMany studies have shown that the abundance level of gene expression is heritable. Analogous to the traditional genetic study, most researchers treat the expression of one gene as a quantitative trait and map it to expression quantitative trait loci (eQTL). This is 1D-trait mapping.
Ker-Chau Li   +3 more
openaire   +4 more sources

Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

open access: yesNature Communications, 2018
Educational attainment and schizophrenia have a negative phenotypic relationship but show positive genetic correlation. Here, the authors study genetic dependence between the two traits and find that multiple genes have pleiotropic effects on both ...
V. Bansal   +12 more
doaj   +1 more source

Exploring the Dimensions of Movement-Specific Reinvestment From Personal Characteristics Perspectives

open access: yesFrontiers in Psychology, 2021
The purposes of the present study were three-fold: to examine (a) if the movement-specific reinvestment responses should be represented as two dimensional constructs, (b) whether dichotomization of the movement-specific reinvestment responses are ...
Masato Kawabata   +2 more
doaj   +1 more source

Identification of Quantitative Trait Loci Determining Vegetative Growth Traits in Coffea Canephor [PDF]

open access: yes, 2011
Recently the use of molecular markers has been successfully applied for some crops. For coffee, new opportunities have been opened since Nestlé R&D Centre in collaboration with ICCRI completed the first genetic map of Coffea canephora. This study was
Crouzillat, C. (Crouzillat)   +2 more
core  

Same traits, different variance : Item-Level Variation Within Personality Measures [PDF]

open access: yes, 2014
© 2014 the Author(s). This article has been published under the terms of the Creative Commons Attribution License. Without requesting permission from the Author or SAGE, you may further copy, distribute, transmit, and adapt the article, with the ...
Altrocchi J.   +5 more
core   +2 more sources

Population and species neighbor identity impact trait–trait relationships and plant performance

open access: yesPopulation Ecology, EarlyView.
We evaluated how populations and species identity influence plant performance and trait outcomes in mixtures, and assessed trait variation among populations of two forb species native to the western United States (Dieteria canescens and Heterotheca villosa) following three interaction treatments (single‐population monoculture, two‐population mixture ...
Alicia J. Foxx   +2 more
wiley   +1 more source

Functional mapping and annotation of genetic associations with FUMA

open access: yesNature Communications, 2017
Prioritizing genetic variants is a major challenge in genome-wide association studies. Here, the authors develop FUMA, a web-based bioinformatics tool that uses a combination of positional, eQTL and chromatin interaction mapping to prioritize likely ...
Kyoko Watanabe   +3 more
doaj   +1 more source

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