Results 61 to 70 of about 1,061,883 (288)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

A Novel Method for Vessel Trajectory Clustering Based on Three-Dimensional Triangulation Division Algorithm

IEEE Access
Automatic identification system (AIS) performs vital functions in vessel collision avoidance and maritime security. The large-scale vessel trajectory data recorded by AIS has been facilitating vessel trajectory pattern mining, of which vessel trajectory ...
Kai Xu, Rui Wang, Qikai Gao, Jingjing Tan   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Adaptive Douglas-Peucker Algorithm With Automatic Thresholding for AIS-Based Vessel Trajectory Compression

IEEE Access, 2019
Automatic identification system (AIS) is an important part of perfecting terrestrial networks, radar systems and satellite constellations. It has been widely used in vessel traffic service system to improve navigational safety. Following the explosion in
Jingxian Liu, Huanhuan Li, Zaili Yang, Kefeng Wu, Yi Liu, Ryan Wen Liu   +5 more
doaj   +1 more source

Online Real-Time Trajectory Analysis Based on Adaptive Time Interval Clustering Algorithm

Big Data Mining and Analytics, 2020
With the development of Chinese international trade, real-time processing systems based on ship trajectory have been used to cluster trajectory in real-time, so that the hot zone information of a sea ship can be discovered in real-time.
Jianjiang Li, Huihui Jiao, Jie Wang, Zhiguo Liu, Jie Wu   +4 more
doaj   +1 more source

Trajectory Clustering and an Application to Airspace Monitoring [PDF]

IEEE Transactions on Intelligent Transportation Systems, 2011
This paper presents a framework aimed at monitoring the behavior of aircraft in a given airspace. Nominal trajectories are determined and learned using data driven methods. Standard procedures are used by air traffic controllers (ATC) to guide aircraft, ensure the safety of the airspace, and to maximize the runway occupancy.
Maxime Gariel, Ashok N. Srivastava, Eric Feron   +2 more
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Trajectory Clustering and Coastal Surveillance

, 2007
In this paper we explore trajectory clustering as a means for representing the normal behavior of vessels in a coastal surveillance scenario. Trajectory clustering however suffers from some drawbacks in this type of setting and we therefore propose a new
Niklasson, Lars, Dahlbom, Anders
core   +1 more source

Trajectory clustering with mixtures of regression models [PDF]

Proceedings of the fifth ACM SIGKDD international conference on Knowledge discovery and data mining, 1999
In this paper we address the problem of clustering trajectories, namely sets of short sequences of data measured as a function of a dependent variable such as time. Examples include storm path trajectories, longitudinal data such as drug therapy response, functional expression data in computational biology, and movements of objects or individuals in ...
Gaffney, Scott, Smyth, Padhraic
openaire   +2 more sources