Results 51 to 60 of about 1,061,883 (288)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
In-DBMS Sampling-based Sub-trajectory Clustering
, 2017 In this paper, we propose an efficient in-DBMS solution for the problem of sub-trajectory clustering and outlier detection in large moving object datasets.
Nikos Pelekis +4 more
core +1 more source
A coarse-to-fine strategy for vehicle motion trajectory clustering [PDF]
, 2006 High-level semantic understanding of vehicle motion behaviors is often based on vehicle motion trajectory clustering. In this paper, we propose an effective trajectory clustering framework in which a coarse-to-fine strategy is taken.
Xi Li +4 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Clustering Indoor Positioning Data Using E-DBSCAN
ISPRS International Journal of Geo-Information, 2021 Indoor positioning data reflects human mobility in indoor spaces. Revealing patterns of indoor trajectories may help us understand human indoor mobility.
Dayu Cheng, Guo Yue, Tao Pei, Mingbo Wu
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Non-Convex Metric Learning-Based Trajectory Clustering Algorithm
MathematicsTo address the issue of suboptimal clustering performance arising from the limitations of distance measurement in traditional trajectory clustering methods, this paper presents a novel trajectory clustering strategy that integrates the bag-of-words model
Xiaoyan Lei, Hongyan Wang
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Deep Trajectory Clustering with Autoencoders
, 2020 International audienceIdentification and characterisation of air traffic flows is an important research topic with many applications areas including decision-making support tools, airspace design or traffic flow management.
Olive, Xavier +3 more
core +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source