Research and Field Testing of CT Short-Radius Sidetracking Technology for Ultra-deep Wells
Shiyou jixie, 2023 Deepening existing wellbores or sidetracking to drill non-produced intervals by means of coiled tubing drilling(CTD)through tubing string can eliminate the cost of tripping out the tubing string and facilitate rapid access to target reservoirs while ...
Wang Juhe, Sun Weiguang, Yu Dongbing
doaj
Safe Robot Trajectory Control Using Probabilistic Movement Primitives and Control Barrier Functions. [PDF]
Front Robot AI, 2022 Davoodi M +4 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
MGA trajectory planning with an ACO-inspired algorithm [PDF]
, 2010 Given a set of celestial bodies, the problem of finding an optimal sequence of swing-bys, deep space manoeuvres (DSM)and transfer arcs connecting the elements of the set is combinatorial in nature.
Vasile, M., Ceriotti, M.
core +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
The Analysis of Trajectory Control of Non-holonomic Mobile Robots Based on Internet of Things Target Image Enhancement Technology and Backpropagation Neural Network. [PDF]
Front Neurorobot, 2021 Zhao L, Wang G, Fan X, Li Y.
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Aging and Cancer, EarlyView.Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Key Technologies and Understanding of Shale Gas Horizontal Well Drilling of Well JY10HF
Shiyou jixie, 2019 Well JY10HF is the first exploratory shale gas horizontal well in the Jinfoshan fault slope of Nanchuan. The developed fracture and cave, large dip angle and poor drillability make it easy to be faced with lost circulation, wellbore collapse, inclination
Fan Hua, Long Zhiping
doaj