Results 91 to 100 of about 18,417,739 (315)

Enhanced 3D Trafficability Analysis for Large‐Volume and Heavy‐Duty Transports Based on High‐Resolution Point Clouds

IET Intelligent Transport Systems
Large‐volume and heavy‐duty transports are essential for the successful and timely execution of large‐scale industrial, socio‐political and climate‐related projects.
Marcus Irmer, Ina Kalder, Marco Tönnemann, René Degen, Lucas Rüggeberg, Karin Thomas, Margot Ruschitzka   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Energy optimization and age of information enhancement in multi‐UAV networks using deep reinforcement learning

Electronics Letters
This letter introduces an innovative approach for minimizing energy consumption in multi‐unmanned aerial vehicles (multi‐UAV) networks using deep reinforcement learning, with a focus on optimizing the age of information (AoI) in disaster environments.
Jeena Kim, Seunghyun Park, Hyunhee Park
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Aeroelastic and Trajectory Control of High Altitude Long Endurance Aircraft

IEEE Transactions on Aerospace and Electronic Systems, 2018
We investigate the aeroelastic and trajectory control of an high altitude long endurance aircraft model in the presence of gust and turbulence disturbances.
Pengyuan Qi, Xiaowei Zhao, Yinan Wang, R. Palacios, A. Wynn   +4 more
semanticscholar   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Kinematic control in a four‐wheeled Mecanum mobile robot for trajectory tracking

The Journal of Engineering
The challenges of the modern world require mobile robots with the ability to navigate in congested environments with high levels of manoeuvrability. Therefore, the Mecanum wheel may be viable for addressing this challenge.
José Carlos Ortiz Hernández, David I. Rosas Almeida   +1 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

A Multi-Terrain Robot Prototype With Archimedean Screw Actuators: Design, Realization, Modeling, and Control

IEEE Access
This work introduces a robot prototype designed to explore locomotion, perception, and navigation in unstructured terrains. The focus of this paper is on the robot’s locomotion, from concept design to realization, as well as modelling and control.
Roza Gkliva, Walid Remmas, Simon Godon, Jaan Rebane, Kilian Ochs, Maarja Kruusmaa, Asko Ristolainen   +6 more
doaj   +1 more source