Results 61 to 70 of about 9,918,357 (236)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Trajectory Planning and Tracking Control of a Differential-Drive Mobile Robot in a Picture Drawing Application

Robotics, 2017
This paper proposes a method for trajectory planning and control of a mobile robot for application in picture drawing from images. The robot is an accurate differential drive mobile robot platform controlled by a field-programmable-gate-array (FPGA ...
Ching-Long Shih, Li-Chen Lin
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

DEVELOPMENT OF TRAJECTORY CONTROL SYSTEM FOR THE OMNIDIRECTIONAL MOBILE ROBOT [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
The article deals with a trajectory control system development for the omnidirectional mobile robot. This kind of robots gives the possibility to control separately each degree of freedom due to special design of the wheels, which greatly facilitates the
Y. A. Kapitanyuk, A. A. Kapitonov, S. A. Chepinsky   +2 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

TRAJECTORY CONTROL OF A SOLID BODY RELATIVE TO THE MOVABLE OBJECT [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
The paper deals with the problem of dynamic tracking of an external movable object. These problems arise when designing tracking control systems for unmanned aircrafts following ground movable objects. A dynamic model of a solid body in three-dimensional
Y. A. Kapitanyuk, D. A. Khvostov, S. A. Chepinsky   +2 more
doaj  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A Conjugate Gradient-Based BPTT-Like Optimal Control Algorithm With Vehicle Dynamics Control Application [PDF]

, 2010
The paper presents a gradient-based algorithm for optimal control of nonlinear multivariable systems with control and state vectors constraints. The algorithm has a backward-in-time recurrent structure similar to the backpropagation-through-time ...
Kolmanovsky, Ilya V., Novakovic, Branko, Joško Deur, Josip Kasac, Kasac, Josip, Francis Assadian, Branko Novakovic, Deur, Josko, Assadian, Francis, Kolmanovsky, Ilya, Ilya V. Kolmanovsky   +10 more
core   +1 more source

A Centralized Multi-Agent DRL-Based Trajectory Control Strategy for Unmanned Aerial Vehicle-Enabled Wireless Communications

IEEE Open Journal of Vehicular Technology
Unmanned aerial vehicles (UAVs) are becoming increasingly popular as mobile base stations due to their flexible deployment and low-cost features, particularly for emergency communications, traffic offloading, and terrestrial communications infrastructure
Getaneh Berie Tarekegn, Rong-Terng Juang, Belayneh Abebe Tesfaw, Hsin-Piao Lin, Huan-Chia Hsu, Robel Berie Tarekegn, Li-Chia Tai   +6 more
doaj   +1 more source