Results 91 to 100 of about 514,814 (311)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
An ant system algorithm for automated trajectory planning
, 2010 The paper presents an Ant System based algorithm to optimally plan multi-gravity assist trajectories. The algorithm is designed to solve planning problems in which there is a strong dependency of one decision one all the previously made decisions. In the
Vasile, M., Ceriotti, M.
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Road Passenger Load Probability Prediction and Path Optimization Based on Taxi Trajectory Big Data
Applied SciencesThis paper focuses on predicting road passenger probability and optimizing taxi driving routes based on trajectory big data. By utilizing clustering algorithms to identify key passenger points, a method for calculating and predicting road passenger ...
Guobin Gu +7 more
doaj +1 more source
Generating Survival Interpretable Trajectories and Data
Doklady MathematicsAbstract A new model for generating survival trajectories and data based on applying an autoencoder of a specific structure is proposed. It solves three tasks. First, it provides predictions in the form of the expected event time and the survival function for a new feature vector based on the Beran estimator ...
Andrei V. Konstantinov +2 more
openaire +3 more sources
A Novel Collision Avoidance Logic for Unmanned Aerial Vehicles Using Real-Time Trajectory Planning [PDF]
, 2014 An effective collision avoidance logic should prevent collision without excessive alerting. This requirement would be even more stringent for an automatic collision avoidance logic, which is probably required by Unmanned Aerial Vehicles to mitigate ...
Lai, Chi Kin
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Trajectory optimization for the Hevelius-lunar microsatellite mission
, 2005 In this paper trajectory optimisation for the Hevelius mission is presented. The Hevelius-Lunar Microsatellite Mission - is a multilander mission to the dark side of the Moon, supported by a relay microsatellite, orbiting on a Halo orbit around L2. Three
Colombo, Camilla +3 more
core
Calibrating Large Scale Vehicle Trajectory Data
, 2012 An accurate and sufficient vehicle trajectory data set is the basis to many trajectory-based data mining tasks and applications. However, vehicle trajectories sampled by GPS devices are usually at a relatively low sampling rate and contain notable ...
Qiong Luo +10 more
core +1 more source