Results 101 to 110 of about 514,814 (311)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Visual analytics of taxi trajectory data via topical sub-trajectories

open access: yesVisual Informatics, 2019
GPS-based taxi trajectories contain valuable knowledge about movement patterns for transportation and urban planning. Topic modeling is an effective tool to extract semantic information from taxi trajectory data. However, previous methods generally ignore trajectory directions that are important in the analysis of movement patterns.
Sichen Jin   +4 more
openaire   +2 more sources

Vehicle trajectory data processed from the Waymo Open Dataset

open access: yes, 2021
This dataset is processed from the Waymo Open Dataset (perception part). This dataset includes the following content: 1. Tabular format object information (Autonomous vehicle and objects detected by Lidar such as vehicles, pedestrians, cyclists) 2 ...
Hu, X (via Mendeley Data)
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Large Scale Evaluation of Normalized Hard-Braking Events Derived from Connected Vehicle Trajectory Data at Signalized Intersections, Roundabouts, and All-Way Stops

open access: yesFuture Transportation
Intersection safety has been traditionally evaluated using three to five years of crash data. Recent literature suggests that connected vehicle (CV)-derived hard braking (HB) events can provide a surrogate for crashes with only a few weeks or months of ...
Vihaan Vajpayee   +3 more
doaj   +1 more source

Real-time detection of traffic congestion based on trajectory data

open access: yesThe Journal of Engineering, 2019
Traffic congestion is common in most cities. It not only affects people's normal travel time but also causes more traffic crashes. To solve the traffic congestion and reduce the corresponding hazards, it is necessary to quickly detect the location of ...
Qing Yang   +5 more
doaj   +1 more source

Online Clustering of Trajectory Data Stream

open access: yes2016 17th IEEE International Conference on Mobile Data Management (MDM), 2016
Movement tracking becomes ubiquitous in many applications, which raises great interests in trajectory data analysis and mining. Most existing approaches cluster the whole trajectories offline. This allows characterizing the past movements of the objects but not current patterns.
Ticiana L. Coelho da Silva   +2 more
openaire   +2 more sources

Algorithms for trajectory integration in multiple views

open access: yes, 2009
PhDThis thesis addresses the problem of deriving a coherent and accurate localization of moving objects from partial visual information when data are generated by cameras placed in di erent view angles with respect to the scene.
Kayumbi-Kabeya, Gabin-Wilfried
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Understanding the Functionality of Human Activity Hotspots from Their Scaling Pattern Using Trajectory Data

open access: yesISPRS International Journal of Geo-Information, 2017
Human activity hotspots are the clusters of activity locations in space and time, and a better understanding of their functionality would be useful for urban land use planning and transportation.
Tao Jia, Zheng Ji
doaj   +1 more source

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