Results 71 to 80 of about 1,376,841 (287)

Anonymizing Trajectory Data: Limitations and Opportunities

, 2022
A variety of conditions and limiting properties complicate the anonymization of trajectory data, since they are sequential, high-dimensional, bound to geophysical restrictions and easily mapped to semantic points of interest and regions with known properties like suburban neighborhoods, industrial areas or city-centers.
Guerra Balboa, Patricia, Miranda Pascual, Àlex, Parra Arnau, Javier, Forné Muñoz, Jorge, Strufe, Thorsten   +4 more
openaire   +4 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Visual analytics of taxi trajectory data via topical sub-trajectories

Visual Informatics, 2019
GPS-based taxi trajectories contain valuable knowledge about movement patterns for transportation and urban planning. Topic modeling is an effective tool to extract semantic information from taxi trajectory data. However, previous methods generally ignore trajectory directions that are important in the analysis of movement patterns.
Huan Liu, Sichen Jin, Yuyu Yan, Yubo Tao, Hai Lin   +4 more
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Characterizing Temporal Patterns of Intra-Urban Human Mobility in Bike-Sharing through Trip Analysis: A Case Study of Shanghai, China

Applied Sciences
Human mobility, encompassing the movement of individuals and/or groups across space and time, significantly impacts various aspects of society, with intra-urban mobility being a major research focus of scholars in diverse disciplines.
Pengdong Zhang, Min Liu, Jinchao Xu, Zhibin Zhu, Ruihan Cao   +4 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Learning from history: Non-Markovian analyses of complex trajectories for extracting long-time behavior [PDF]

, 2014
A number of modern sampling methods probe long time behavior in complex biomolecules using a set of relatively short trajectory segments. Markov state models (MSMs) can be useful in analyzing such data sets, but in particularly complex landscapes, the ...
Suarez, Ernesto, Zuckerman, Daniel
core  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Road Passenger Load Probability Prediction and Path Optimization Based on Taxi Trajectory Big Data

Applied Sciences
This paper focuses on predicting road passenger probability and optimizing taxi driving routes based on trajectory big data. By utilizing clustering algorithms to identify key passenger points, a method for calculating and predicting road passenger ...
Guobin Gu, Benxiao Lou, Dan Zhou, Xiang Wang, Jianqiu Chen, Tao Wang, Huan Xiong, Yinong Liu   +7 more
doaj   +1 more source