Results 81 to 90 of about 449,739 (281)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Prediction of Drag Anchor Trajectory Considering Both Shallow and Deep Anchor Behavior of Inclined Fluke

Journal of Marine Science and Engineering
The prediction of drag anchor trajectory is key for the anchor design. The yield envelope method based on anchor behavior under combined loadings provided an alternative method for the prediction of anchor trajectory.
Xiaoni Wu, Chao Tang, Zihao Jiang, Jinjian Chen, Teng Wang, Jian Shu   +5 more
doaj   +1 more source

Transferable Pedestrian Motion Prediction Models at Intersections

, 2019
One desirable capability of autonomous cars is to accurately predict the pedestrian motion near intersections for safe and efficient trajectory planning.
Habibi, Golnaz, How, Jonathan P., Shen, Macheng   +2 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Hypersonic glide vehicle trajectory prediction based on frequency enhanced channel attention and light sampling-oriented MLP network

Defence Technology
Hypersonic Glide Vehicles (HGVs) are advanced aircraft that can achieve extremely high speeds (generally over 5 Mach) and maneuverability within the Earth's atmosphere.
Yuepeng Cai, Xuebin Zhuang
doaj   +1 more source

Certified Human Trajectory Prediction

2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
Predicting human trajectories is essential for the safe operation of autonomous vehicles, yet current data-driven models often lack robustness in case of noisy inputs such as adversarial examples or imperfect observations. Although some trajectory prediction methods have been developed to provide empirical robustness, these methods are heuristic and do
Bahari, Mohammadhossein, Saadatnejad, Saeed, Farsangi, Amirhossein Askari, Moosavi-Dezfooli, Seyed-Mohsen, Alahi, Alexandre   +4 more
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

TribeFlow

Proceedings of the 25th International Conference on World Wide Web, 2016
Which song will Smith listen to next? Which restaurant will Alice go to tomorrow? Which product will John click next? These applications have in common the prediction of user trajectories that are in a constant state of flux over a hidden network (e.g. website links, geographic location).
Figueiredo, Flavio, Ribeiro, Bruno, Almeida, Jussara, Faloutsos, Christos   +3 more
openaire   +2 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Multiobjective Tactical Planning under Uncertainty for Air Traffic Flow and Capacity Management [PDF]

, 2013
We investigate a method to deal with congestion of sectors and delays in the tactical phase of air traffic flow and capacity management. It relies on temporal objectives given for every point of the flight plans and shared among the controllers in order ...
Marceau, Gaétan, Savéant, Pierre, Schoenauer, Marc   +2 more
core   +2 more sources