Results 51 to 60 of about 2,377,503 (288)

Report on trajectory analysis and optimization of the nominal flight trajectory and sensitivities [PDF]

, 2011
This deliverable presents work done on the optimization of the nominal flight of the SpaceLiner (a flight from Sydney to Western Europe). Optimality is measured with respect to the total take-off mass of the SpaceLiner. The main parameter is therefore propellant mass.
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Elliposoidal estimates of trajectory sensitivity of multi-dimensional processes based on generalized singular values problems

Научно-технический вестник информационных технологий, механики и оптики
The problem of studying the sensitivity of control processes to parameter variations is considered. To solve the problem, the trajectory sensitivity apparatus was used, the use of which, together with the state-space method, made it possible to construct
R. O. Omorov, T. A. Akunov, A. O. Aidraliev   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The association between fluid balance trajectories and prognosis in ICU patients with cardiac arrest, a group-based trajectory model analysis

Frontiers in Nutrition
BackgroundThe impact of dynamic fluid balance (FB) changes on the prognosis of ICU patients with cardiac arrest (CA) remains unclear. This study aims to explore the association between FB trajectories and the prognosis of such patients.MethodsData were ...
Qitian Zhang, Guangyu Lin, Chunmei Zhang
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Collaborative offloading for UAV-enabled time-sensitive MEC networks

EURASIP Journal on Wireless Communications and Networking, 2021
Recently, unmanned aerial vehicle (UAV) acts as the aerial mobile edge computing (MEC) node to help the battery-limited Internet of Things (IoT) devices relieve burdens from computation and data collection, and prolong the lifetime of operating. However,
Wen-Tao Li, Mingxiong Zhao, Yu-Hui Wu, Jun-Jie Yu, Ling-Yan Bao, Huan Yang, Di Liu   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Algorithms for trajectory integration in multiple views [PDF]

, 2009
PhDThis thesis addresses the problem of deriving a coherent and accurate localization of moving objects from partial visual information when data are generated by cameras placed in di erent view angles with respect to the scene.
Kayumbi-Kabeya, Gabin-Wilfried
core   +4 more sources