Results 71 to 80 of about 2,377,503 (288)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Association between hemoglobin-to-red blood cell distribution width ratio trajectory patterns and in-hospital mortality in critically ill patients with cirrhosis: a retrospective cohort study based on MIMIC-IV and eICU-CRD

BMC Medical Informatics and Decision Making
Background Critically ill patients with cirrhosis face an elevated risk of mortality. The hemoglobin-to-red blood cell distribution width ratio (HRR) has emerged as a potential biomarker in various critical illnesses. However, the prognostic significance
Zhikai Zhang, Guangren Peng, Meihua Zhou, Xiaomin Lu   +3 more
doaj   +1 more source

Group-based trajectory modeling under non-random attrition: A sensitivity analysis and application to frailty trajectories

Methods in Psychology
Group-based trajectory modeling (GBTM) is used to identify trajectories but suffers from attrition bias when dropout is non-random. We evaluate an extended GBTM that models attrition as a latent-class process.
Chendong Li, Depeng Jiang, Philip St John, Robert Tate   +3 more
doaj   +1 more source

TCSC control design for transient stability improvement of a multi-machine power system using trajectory sensitivity

, 2007
This paper discusses the effects of thyristor controlled series compensator (TCSC), a series FACTS controller, on the transient stability of a power system.
Chatterjee, Dheeman, Ghosh, Arindam
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Fluid balance trajectories and prognosis in patients with acute myocardial infarction complicated by cardiogenic shock: a group-based trajectory model approach

Frontiers in Cardiovascular Medicine
BackgroundFluid management is crucial in the treatment of patients with acute myocardial infarction complicated by cardiogenic shock (AMI-CS), yet the optimal strategy remains unclear. This study aims to evaluate the association between fluid balance (FB)
Chunmei Zhang, Zhiyi Xie, Guangyu Lin, Qitian Zhang   +3 more
doaj   +1 more source

Differential privacy protection method based on published trajectory cross-correlation constraint.

PLoS ONE, 2020
Aiming to solve the problem of low data utilization and privacy protection, a personalized differential privacy protection method based on cross-correlation constraints is proposed.
Zhaowei Hu, Jing Yang
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Application of Trajectory Sensitivity for the Evaluation of the Effect of TCSC Placement on Transient Stability [PDF]

, 2007
This paper investigates the use of trajectory sensitivity analysis (TSA) technique for assessing the transient stability of a power system at various operating conditions.
Chatterjee, Dheeman, Ghosh, Arindam
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source