Results 81 to 90 of about 2,377,503 (288)

Sensitivity Analysis of MTPA Control to Angle Errors for Synchronous Reluctance Machines

Mathematics
This study investigated the sensitivity of maximum torque per ampere (MTPA) control in synchronous reluctance machines (SynRMs) to angle errors, examining specifically how deviations in the reference control trajectory affected performance.
Martin Petrun, Jernej Černelič
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Quantum enhanced metrology based on flipping trajectory of cold Rydberg gases

Nature Communications
The dynamical trajectory of a dissipative Rydberg many-body system could be flipped under a microwave field driving, displaying an enhanced sensitivity. This is because the intersection of the folded hysteresis trajectories exhibits a sharp peak near the
Ya-Jun Wang, Jun Zhang, Zheng-Yuan Zhang, Shi-Yao Shao, Qing Li, Han-Chao Chen, Yu Ma, Tian-Yu Han, Qi-Feng Wang, Jia-Dou Nan, Yi-Ming Yin, Dong-Yang Zhu, Qiao-Qiao Fang, Chao Yu, Xin Liu, Guang-Can Guo, Bang Liu, Li-Hua Zhang, Dong-Sheng Ding, Bao-Sen Shi   +19 more
doaj   +1 more source

Longitudinal study on health-related quality of life and multimorbidity: from trajectories to outcomes in China

Frontiers in Public Health
BackgroundThe association between multimorbidity and health-related quality of life has been extensively studied. This study aimed to investigate the longitudinal association between multimorbidity and health-related quality of life in a rural Chinese ...
Jiancai Du, Jiancai Du, Jiancai Du, Ai Qi, Ai Qi, Ai Qi, Wenlong Wang, Wenlong Wang, Ximin Ma, Ximin Ma, Jiahui He, Jiahui He, Qi Hu, Qi Hu, Kexin Chen, Kexin Chen, Hui Qiao, Hui Qiao   +17 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Second-Order Trajectory Sensitivity Analysis of Hybrid Systems

IEEE Transactions on Circuits and Systems I: Regular Papers, 2019
Hybrid dynamical systems are characterized by intrinsic coupling between continuous dynamics and discrete events. This paper has adopted a differential-algebraic impulsive switched (DAIS) model to capture such dynamic behavior. For such systems, trajectory sensitivity analysis provides a valuable approach for describing perturbations of system ...
Sijia Geng, Ian A. Hiskens
openaire   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source