Group 2 Innate Lymphoid Cells in Respiratory Allergic Inflammation [PDF]
, 2019 Millions of people worldwide are suffering from allergic inflammatory airway disorders. These conditions are regarded as a consequence of multiple imbalanced immune events resulting in an inadequate response with the exact underlying mechanisms still ...
Duerr, Claudia U. +3 more
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Precision Medicine in Targeted Therapies for Severe Asthma:Is There Any Place for "omics" Technology? [PDF]
, 2018 According to the current guidelines, severe asthma still represents a controversial topic in terms of definition and management. The introduction of novel biological therapies as a treatment option for severe asthmatic patients paved the way to a ...
Bertolini, Francesca +6 more
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Portuguese recommendations for the treatment of atopic dermatitis with biologic therapy and JAK inhibitors in adult patients [PDF]
, 2021 Funding Information: Disclosure and potential conflicts of interest: TT has received research grants and/or consulting fees from AbbVie, Almirall, Amgen, Arena Pharmaceuticals, Biocad, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Eli Lilly ...
Bastos, Pedro Mendes +10 more
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Reduced epithelial suppressor of cytokine signalling 1 in severe eosinophilic asthma [PDF]
, 2016 Severe asthma represents a major unmet clinical need. Eosinophilic inflammation persists in the airways of many patients with uncontrolled asthma, despite high-dose inhaled corticosteroid therapy. Suppressors of cytokine signalling (SOCS) are a family of
Arron, Joseph R +9 more
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Dupilumab: A new paradigm for the treatment of allergic diseases [PDF]
, 2018 Moderate and severe forms of allergic diseases such as atopic dermatitis and asthma are a challenge for clinicians. In these conditions, which severely affect the quality of life of the patient and frequently have associated allergic comorbidities, the ...
Dávila, Ignacio, Sastre, Joaquín
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Immunoglobulin G; structure and functional implications of different subclass modifications in initiation and resolution of allergy. [PDF]
, 2017 IgE and not IgG is usually associated with allergy. IgE lodged on mast cells in skin or gut and basophils in the blood allows for the prolonged duration of allergy through the persistent expression of high affinity IgE receptors.
Amlot P. L. +18 more
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Targeting Interleukin 13 for the Treatment of Atopic Dermatitis
Pharmaceutics, 2023 Atopic dermatitis (AD) is a common chronic inflammatory skin condition that has a significant impact on a patient’s quality of life and requires ongoing management.
Yuliya Lytvyn, Melinda Gooderham
doaj +1 more source
Medical therapy of stricturing Crohn’s disease: what the gut can learn from other organs - a systematic review [PDF]
, 2014 Crohn’s disease (CD) is a chronic remitting and relapsing disease. Fibrostenosing complications such as intestinal strictures, stenosis and ultimately obstruction are some of its most common long-term complications.
Dominik Bettenworth, Florian Rieder
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Updated Review on Treatment of Atopic Dermatitis [PDF]
, 2023 La dermatitis atópica (DA) es una dermatosis inflamatoria crónica o crónicamente recurrente, asociada a múltiples desencadenantes y con un mecanismo fisiopatológico complejo. Se caracteriza por una expresión clínica, signos y síntomas heterogéneos.
Armario Hita, José Carlos +4 more
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Frontiers in Medicine, 2023 Atopic dermatitis (AD) is a chronic inflammatory disease with a heterogeneous pathogenesis correlated with dysregulation of the immune system and a prevalence of the T2-mediated immune pathway.
Carlo Caffarelli +3 more
doaj +1 more source