Results 231 to 240 of about 7,801 (328)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Bridging the gap in fishing effort mapping: a spatially-explicit fisheries dataset for Campanian MPAs, Italy. [PDF]
Lattanzi P +6 more
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
State of the art modelling for the Black Sea ecosystem to support European policies. [PDF]
Serpetti N +5 more
europepmc +1 more source
Central-Positive Complexes: A Novel Characterization of Ictal Markers Induced During Electroconvulsive Therapy. [PDF]
Hogan RE +4 more
europepmc +1 more source
On Sweeping Trammel Net Fishery along the Coast in the San'in District-V
Takeru Kitahara
openalex +2 more sources
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
The environmental friendliness level of the trammel net in Kuala Langsa, Langsa City, Aceh Province
Anania Rahmah +3 more
openalex +1 more source

