Results 11 to 20 of about 5,120,986 (304)

Tranexamic Acid to Prevent Obstetrical Hemorrhage after Cesarean Delivery.

New England Journal of Medicine, 2023
BACKGROUND Prophylactic use of tranexamic acid at the time of cesarean delivery has been shown to decrease the calculated blood loss, but the effect on the need for blood transfusions is unclear.
L. Pacheco, R. Clifton, G. Saade, Steven J. Weiner, S. Parry, J. Thorp, M. Longo, A. Salazar, W. Dalton, Alan T N Tita, C. Gyamfi‐Bannerman, S. Chauhan, T. Metz, K. Rood, D. Rouse, J. Bailit, W. Grobman, H. Simhan, G. Macones   +18 more
semanticscholar   +1 more source

Tranexamic acid in melasma: A focused review on drug administration routes

Journal of Cosmetic Dermatology, 2023
Melasma is a disorder of hyperpigmentation and vascularization often found in women between the ages of 20 and 40. The pathogenesis is unknown, but melasma often occurs in sun‐exposed areas of the face, forearms, and back.
Hailey Konisky, Eliza Balazic, J. Jaller, Urmi Khanna, K. Kobets   +4 more
semanticscholar   +1 more source

Effect of tranexamic acid administration on intraoperative blood loss during peritonectomy: a single-center retrospective observational study

JA Clinical Reports, 2023
Background The efficacy of tranexamic acid in elective major invasive abdominal surgeries has not yet been established. We investigated the effect of tranexamic acid administration on intraoperative blood loss during peritoneal resection of ...
Daiki Shirasu, Masahiko Tsuchiya, Noriaki Oomae, Wataru Shirasaka, Tatsuhiko Iino, Daisuke Hirano, Makoto Satani   +6 more
doaj   +1 more source

Tranexamic acid for haemostasis and beyond: does dose matter?

Thrombosis Journal, 2023
Tranexamic acid (TXA) is a widely used antifibrinolytic agent that has been used since the 1960’s to reduce blood loss in various conditions. TXA is a lysine analogue that competes for the lysine binding sites in plasminogen and tissue-type plasminogen ...
Tammy Lam, R. Medcalf, Geoffrey C. Cloud, Paul S. Myles, Charithani B. Keragala   +4 more
semanticscholar   +1 more source

Tranexamic acid-induced focal convulsions after spinal surgery: a rare case report and literature review on side effects of accidental spinal administration of tranexamic acid

EFORT Open Reviews, 2023
Convulsions are a neurological illness that has complexity. In clinical treatment, drug-induced convulsions appear from time to time. Drug-induced convulsions often begin as isolated acute seizures but may progress to persistent seizures. In orthopedics,
Hua Luo, Chaojun Shen, Tongyou Qu, Lin Chen, Yue Sun, Yu Ren   +5 more
doaj   +1 more source

Poster 84: Tranexamic Acid Use in Hip Arthroscopy: A Triple-Blind, Randomized, Placebo-Controlled Trial [PDF]

Orthop J Sports Med
Kyle N. Kunze, Sophia J. Madjarova, Reena Olsen, Ryan Smolarsky, Anil S. Ranawat, Danyal H. Nawabi, Bryan T. Kelly, Benedict U. Nwachukwu   +7 more
europepmc   +2 more sources

Tranexamic acid, as an adjunct to oxytocin prophylaxis, in the prevention of postpartum haemorrhage in women undergoing elective caesarean section: A single‐centre double‐blind randomised controlled trial

BJOG: an International Journal of Obstetrics and Gynaecology, 2023
To evaluate the effectiveness of tranexamic acid (TXA) in reducing blood loss during elective caesarean sections in women with and without risk factors for postpartum haemorrhage (PPH).
S. Lee, M. Kwek, S. Tagore, A. Wright, C. W. Ku, A. Teong, A. Tan, S. W. C. Lim, D. Yen, C. Ang, R. Sultana, C. H. F. Lim, D. Mathur, M. Mathur   +13 more
semanticscholar   +1 more source

Prophylactic intravenous tranexamic acid and thromboembolism in non-cardiac surgery: a systematic review, meta-analysis and trial sequential analysis.

Anaesthesia, 2023
Tranexamic acid is an antifibrinolytic drug that is widely used during surgery, but there are concerns about its thromboembolic effects. We aimed to investigate the effect of prophylactic intravenous tranexamic acid on thromboembolic outcomes in patients
S. Tsan, N. L. Viknaswaran, C. C. Cheong, S. Cheah, K. Ng, S. Mong, C. Y. Wang   +6 more
semanticscholar   +1 more source

Tranexamic Acid in Patients Undergoing Noncardiac Surgery.

New England Journal of Medicine, 2022
BACKGROUND Perioperative bleeding is common in patients undergoing noncardiac surgery. Tranexamic acid is an antifibrinolytic drug that may safely decrease such bleeding.
P. Devereaux, M. Marcucci, T. Painter, D. Conen, V. Lomivorotov, D. Sessler, M. Chan, F. Borges, M. Martínez-Zapata, Chew-Yin Wang, Denis Xavier, S. Ofori, M. Wang, S. Efremov, G. Landoni, Y. Kleinlugtenbelt, W. Szczeklik, D. Schmartz, A. Garg, T. Short, M. Wittmann, C. Meyhoff, M. Amir, David Torres, Ameen Patel, E. Duceppe, K. Ruetzler, J. Parlow, V. Tandon, E. Fleischmann, C. Polanczyk, A. Lamy, S. Astrakov, Mangala Rao, William K K Wu, K. Bhatt, M. de Nadal, V. Likhvantsev, P. Paniagua, H. Aguado, R. Whitlock, M. McGillion, M. Prystajecky, J. Vincent, J. Eikelboom, I. Copland, K. Balasubramanian, A. Turan, S. Bangdiwala, David Stillo, Peter Gross, T. Cafaro, P. Alfonsi, P. Roshanov, E. Belley‐Cote, J. Spence, T. Richards, T. Vanhelder, William L. McIntyre, G. Guyatt, S. Yusuf, K. Leslie   +61 more
semanticscholar   +1 more source

Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. [PDF]

, 2020
OBJECTIVE: To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS: We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered
Arulkumaran, S, Balakumar, S, Muhunthan, K, Navaratnaraja, TS, Premakrishna, S   +4 more
core   +1 more source