Results 11 to 20 of about 33,417 (194)

Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study [PDF]

, 2007
Objective: Postoperative bleeding is still one of the most common complications of cardiac surgery. Antifibrinolytic agents successfully reduce bleeding, but there are controversies concerning adverse effects after their systemic use.
Barić, Davor, Bačić Vrca, Vesna, Biočina, Bojan, Brkić, Kristina, Ivković, Mira, Rudež, Igor, Sutlić, Željko, Unić, Daniel   +7 more
core   +1 more source

Circulatory contributors to the phenotype in hereditary hemorrhagic telangiectasia [PDF]

, 2015
Hereditary hemorrhagic telangiectasia (HHT) is mechanistically and therapeutically challenging, not only because of the molecular and cellular perturbations that generate vascular abnormalities, but also the modifications to circulatory physiology that ...
Shovlin, CL
core   +2 more sources

The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial. [PDF]

, 2018
BACKGROUND: In severe post-partum haemorrhage, death can occur within hours of bleeding onset so interventions to control the bleeding must be given immediately.
A Godier, A Pilbrant, Amy Brenner, BE Yee, Bukola Fawole, DJ Fletcher, H Shakur, H Shakur, Haleema Shakur-Still, I Roberts, Ian Roberts, K Ker, KJ Rothman, L Andersson, L Andersson, MA Hernán, R Fears, Rizwana Chaudhri, Sabaratnam Arulkumaran, WOMAN Trial Collaborators   +19 more
core   +2 more sources

Tranexamic acid therapy in pediatric cardiac surgery:a single center study [PDF]

, 2012
Background: We conducted a retrospective study of cyanotic and acyanotic patients undergoing cardiopulmonary bypass to determine the effect of tranexamic acid on blood loss and blood products administered during the operation in pediatric cardiac surgery.
Cioffi S, Giordano R, MANNACIO, VITO ANTONIO, Mucerino M, PALMA, GAETANO, Palumbo S, Poli V, Russolillo V, VOSA, CARLO   +8 more
core   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation [PDF]

, 2020
Introduction: Patients with trauma-induced coagulopathies may benefit from the use of antifibrinolytic agents, such as tranexamic acid (TXA). This study evaluated the safety and efficacy of TXA in civilian adults hospitalized with traumatic hemorrhagic ...
Borger, Rodney, Chandwani, Deepak, Comunale, Mark E., Dong, Fanglong, Inaba, Kenji, Lowe, Andrew, Neeki, Michael, Powell, Joe, Quispe, Juan, Rabiei, Massoud, Salameh, Joseph, Toy, Jake, Vara, Richard, Wong, David   +13 more
core  

Closure of the nasal cavities in the treatment of refractory hereditary haemorrhagic telangiectasia [PDF]

, 1997
From a cohort of 35 patients with hereditary haemorrhagic telangiectasia (HHT), 12 patients have undergone closure of the one or both nasal cavities during the last three years for refractory epistaxis.
Howard, DJ, Lund, VJ
core   +1 more source

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): protocol and statistical analysis plan for a randomized controlled trial. [PDF]

, 2016
Background: Postpartum haemorrhage (PPH) is a leading cause of maternal death. Tranexamic acid has the potential to reduce bleeding and a large randomized controlled trial of its effect on maternal health outcomes in women with PPH (The WOMAN trial) is ...
Aimakhu, Chris O, Bello, Adenike, Fawole, Bukola, Gregg, Meghann, Huque, Sumaya, Kotila, Taiwo, Kuti, Modupe, Ogunbode, Olayinka, Olayemi, Oladapo, Roberts, Ian, Shakur, Haleema   +10 more
core   +2 more sources

Tranexamic Acid Use in Hip Arthroscopy Reduces Bleeding Without Increased Risk of Major Complications: A Systematic Review

Arthroscopy, EarlyView.
Purpose To critically evaluate the impact of tranexamic acid (TXA) on hip arthroscopy outcomes, including its effects on bleeding, functional recovery, postoperative pain, complications, intraoperative visualization, and surgical efficiency. Methods A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic ...
Paul B. Walker, Mathangi Sridharan, Adrian Lin, Atousa Nourmahnad, Alexander Fish, Sharon L. Hame, Kristofer J. Jones   +6 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source