Results 221 to 230 of about 5,005,447 (264)
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Prehospital Tranexamic Acid for Severe Trauma.
New England Journal of Medicine, 2023BACKGROUND Whether prehospital administration of tranexamic acid increases the likelihood of survival with a favorable functional outcome among patients with major trauma and suspected trauma-induced coagulopathy who are being treated in advanced trauma ...
R. Gruen +22 more
semanticscholar +1 more source
Expert Opinion on Drug Delivery, 2023
Introduction Tranexamic acid is used for the treatment of hyperpigmentation, and the topical route is the most favorable route for its administration. Tranexamic acid lowers plasmin and tyrosinase, which reduces melanin and skin hyperpigmentation.
P. Verma, K. Yadav
semanticscholar +1 more source
Introduction Tranexamic acid is used for the treatment of hyperpigmentation, and the topical route is the most favorable route for its administration. Tranexamic acid lowers plasmin and tyrosinase, which reduces melanin and skin hyperpigmentation.
P. Verma, K. Yadav
semanticscholar +1 more source
Tranexamic acid for trauma [PDF]
The Lancet, 2011 The CRASH-2 trial (July 3, p 23) showed reduced trauma mortality through the simple and cheap inter vention of tranexamic acid, placing it into a growing list of options for managing the acute coagulopathy of trauma. This list includes fresh frozen plasma, cryoprecipitate, platelets, fi brinogen, thrombin, prothrombin complexes, recombinant factor VIIa,
Russell L. Gruen, Biswadev Mitra
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Air Medical Journal, 2022
Tranexamic acid (TXA) has demonstrated a reduction in all-cause mortality in trauma patients with hemorrhage. Administering TXA in the prehospital setting presents unique challenges because the identification of bleeding is based on clinical suspicion without advanced imaging or diagnostic tools.
Joseph DeVitis +12 more
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Tranexamic acid (TXA) has demonstrated a reduction in all-cause mortality in trauma patients with hemorrhage. Administering TXA in the prehospital setting presents unique challenges because the identification of bleeding is based on clinical suspicion without advanced imaging or diagnostic tools.
Joseph DeVitis +12 more
openaire +2 more sources
The uses of tranexamic acid in dermatology: a review
International Journal of Dermatology, 2022Tranexamic acid is a plasmin inhibitor that is used off‐label for the treatment of melasma. The use of tranexamic acid has expanded in the field of dermatology based on its anti‐inflammatory and anti‐melanin‐producing properties, which include the ...
Katelyn M Kim, H. Lim
semanticscholar +1 more source
Use of Tranexamic Acid in Liposculpture: A Double-Blind, Multicenter, Randomized Clinical Trial
Plastic and Reconstructive Surgery, 2022Background: Intraoperative hemostasis should be performed with great caution because bleeding is a huge enemy of patient safety during surgery. Tranexamic acid is a lysine synthetic derivate that inhibits fibrinolysis and diminishes the bleeding by ...
Alfredo E. Hoyos +9 more
semanticscholar +1 more source
Tranexamic acid for percutaneous nephrolithotomy
Cochrane Database of Systematic Reviews, 2022Percutaneous nephrolithotomy (PCNL) is the gold standard for the treatment of large kidney stones but comes with an increased risk of bleeding compared to other treatments, such as ureteroscopy and shock wave lithotripsy. Tranexamic acid (TXA) is an antifibrinolytic agent that has been used to reduce bleeding complications in other settings.To assess ...
Brent, Cleveland +7 more
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Annals of Pharmacotherapy, 1996
Tranexamic acid has the potential to be a pharmacologic adjunct for the prophylaxis of hemorrhagic complications occurring in the oncology population. The studies and cases reviewed here suggest that tranexamic acid administration may be a therapeutic option for bleeding prophylaxis in APL where enhanced fibrinolysis accompanies the disease state ...
Arnold H. Seto, Donna S Dunlap
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Tranexamic acid has the potential to be a pharmacologic adjunct for the prophylaxis of hemorrhagic complications occurring in the oncology population. The studies and cases reviewed here suggest that tranexamic acid administration may be a therapeutic option for bleeding prophylaxis in APL where enhanced fibrinolysis accompanies the disease state ...
Arnold H. Seto, Donna S Dunlap
openaire +2 more sources
Tranexamic Acid in Pediatric Scoliosis Surgery
Spine, 2021In this randomized trial that included 166 adolescent idiopathic scoliosis patients aged between 10 to 21 years old who underwent posterior spinal fusion surgery with a mean duration of 120 minutes by two attending surgeons in a single academic ...
M. Hasan +5 more
semanticscholar +1 more source