Results 21 to 30 of about 26,721 (231)

Efficacy Of Tranexamic Acid in Reducing Blood Loss in Primary Total Knee Replacement

Journal of Rawalpindi Medical College, 2023
Objective: To determine the efficacy of tranexamic acid in reducing blood loss in primary total knee replacement. Material and Methods: A total of 96 patients having a diagnosis of primary knee osteoarthritis made up the population sample.
Muhammad Inaamullah Younas, Faizan Rauf, Muhammad Sheraz Mustafa, Sarmad Nasir Janjua, Shaheen Iqbal, Khurram Habib   +5 more
doaj   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

British Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá, Luisa Barreiros, Marcela A. Segundo, Eugénia Cruz, Sibylle Langenecker   +4 more
wiley   +1 more source

Prehospital tranexamic acid for trauma victims

Journal of Intensive Care, 2023
The public enquiry into the mass casualty incident at the Manchester Arena in the UK in which 23 people died and over 1000 were injured, identified the need for timely intramuscular administration of tranexamic acid to trauma patients.
Kazuhiko Omori, Ian Roberts
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Use of tranexamic acid for skin whitening and melasma therapy: A product review

Archives of Pharmacy Practice, 2016
Purpose: The aim of this study is to assess the usage of tranexamic acid as skin whitening and melasma therapy. Methodology: An electronic search on PubMed, MEDLINE and Cochrane Library with keywords “tranexamic acid,” “oral,” “systemic,” “whitening ...
Halimi Syafiqah Nadiah, Masood Hannah, Kah Seng Lee, Suhaidah Mohd Jofrry, Long Chiau Ming   +4 more
doaj   +1 more source

The efficacy and safety of intravenous tranexamic acid in patients with posterior operation of multilevel thoracic spine stenosis: a prospective randomized controlled trial

BMC Musculoskeletal Disorders, 2022
Background This study was a randomized controlled trial to evaluate efficacy and safety of the usage of intravenous tranexamic acid during posterior operation of multilevel thoracic spine stenosis for controlling perioperative blood loss.
Tan Lei, Wen Bingtao, Guo Zhaoqing, Chen Zhongqiang, Liu Xin   +4 more
doaj   +1 more source

Reducing blood loss during open myomectomy with intravenous versus topical tranexamic acid: A double-blinded randomized placebo-controlled trial

Middle East Fertility Society Journal, 2018
Objectives: To assess the effect of Intravenous versus Topical Tranexamic acid in reducing intra-operative and post-operative blood loss in abdominal myomectomy surgeries.
Nahla W. Shady, Hany F. Sallam, Huda Fahmy   +2 more
doaj   +1 more source

Gastric antral vascular ectasia: A rare etiology of gastrointestinal bleeding in children

JPGN Reports, EarlyView.
Abstract Gastrointestinal bleeding is relatively common in children. While most patients present with mild bleeding, gastric antral vascular ectasia (GAVE) is a rare but potentially life‐threatening cause. GAVE is typically associated with chronic conditions and more common in adults.
Omar Alharbi, Sindhura Kasturi, George Yanni, Blake Rosenthal   +3 more
wiley   +1 more source

A randomized control trial to evaluate the effectiveness of intravenous, intra-articular and topical wash regimes of tranexamic acid in primary total knee arthroplasty

Journal of Orthopaedic Surgery, 2017
Background: The efficacy of tranexamic acid to decrease post-operative blood loss and blood transfusion is well established in literature. However, the ideal mode of administration is debatable.
Jatin Prakash, Jong-Keun Seon, Yong Jin Park, Cheng Jin, Eun-Kyoo Song   +4 more
doaj   +1 more source