Results 21 to 30 of about 5,023,654 (293)
Plastic and Reconstructive Surgery, 2022 Background: Although high-bleed surgery routinely utilizes the antifibrinolytic drug tranexamic acid, most plastic surgical procedures are conducted in soft tissue with low-volume bleeding.
Kjersti Ausen +3 more
semanticscholar +1 more source
Chinese Neurosurgical Journal, 2020 To conduct a systematic review and meta-analysis and evaluate the effect of tranexamic acid in patients with traumatic brain injury. PubMed, EMBASE, and CENTRAL (Cochrane Central Register of Controlled Trials) were searched to identify randomized ...
Chao-nan Du +3 more
doaj +1 more source
The effect of Tranexamic acid on cardiac surgery bleeding [PDF]
Reviews in Clinical Medicine, 2014 Serious bleeding in cardiac surgery leads to re-exploration, blood transfusion and increases the risks of mortality and morbidity. Using the lysine analogous of antifibrionlytic agents are the preferred strategy to suppress the need for transfusion ...
Mohammad Esmaeelzadeh, Shahram Amini
doaj +3 more sources
Comparative Study of Two Different Intravenous Doses of Tranexamic Acid with Placebo on Surgical Field Quality in Functional Endoscopic Sinus Surgery-A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Intraoperative haemorrhage, which disrupts surgical patency, is a major obstacle for surgeons, especially in endoscopic sinus surgeries. Tranexamic acid is synthetic antifibrinolytic agent that binds competitively at lysine binding site on ...
Tamil Anbu Pannerselvam +2 more
doaj +1 more source
Tranexamic acid for surgical bleeding [PDF]
BMJ, 2014 Uncertainty over vascular occlusive events warrants an adequately powered RCT Joint replacement accounts for a large share of the 230 million major operations carried out each year worldwide. Each year in England and Wales alone there are about 180 000 hip and knee replacements.1 Bleeding is an important complication, and many patients require a blood
Ian Roberts, Katharine Ker
openaire +3 more sources
Critical Care, 2021 Background Tranexamic acid (TXA) reduces surgical bleeding and reduces death from bleeding after trauma and childbirth. However, its effects on thrombotic events and seizures are less clear.
Shuhei Murao +3 more
semanticscholar +1 more source
Frontiers in Surgery, 2022 Tranexamic acid has been shown to reduce rebleeding after aneurysmal subarachnoid hemorrhage; however, whether it can reduce mortality and improve clinical outcomes is controversial.
Min Shi +4 more
semanticscholar +1 more source
Trials, 2022 Background The prophylactic administration of tranexamic acid reduces blood loss during procedures at high risk of perioperative bleeding. Several studies in cardiac surgery and orthopedics confirmed this finding.
M. Balik +5 more
doaj +1 more source
Tranexamic acid evidence and controversies: An illustrated review
Research and Practice in Thrombosis and Haemostasis, 2021 Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding, trauma, postpartum hemorrhage, traumatic brain injury, and surgical site ...
Nicole Relke +2 more
semanticscholar +1 more source
Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients
Anesthesiology, 2021 Background: With increasing use of tranexamic acid in total hip and knee arthroplasties, safety concerns remain. Using national claims data, this study examined tranexamic acid use in patients with preexisting comorbidities.
J. Poeran +5 more
semanticscholar +1 more source