Results 21 to 30 of about 5,005,447 (264)
Comparative Study of Two Different Intravenous Doses of Tranexamic Acid with Placebo on Surgical Field Quality in Functional Endoscopic Sinus Surgery-A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Intraoperative haemorrhage, which disrupts surgical patency, is a major obstacle for surgeons, especially in endoscopic sinus surgeries. Tranexamic acid is synthetic antifibrinolytic agent that binds competitively at lysine binding site on ...
Tamil Anbu Pannerselvam +2 more
doaj +1 more source
Critical Care, 2021 Background Tranexamic acid (TXA) reduces surgical bleeding and reduces death from bleeding after trauma and childbirth. However, its effects on thrombotic events and seizures are less clear.
Shuhei Murao +3 more
semanticscholar +1 more source
Tranexamic acid for surgical bleeding [PDF]
BMJ, 2014 Uncertainty over vascular occlusive events warrants an adequately powered RCT Joint replacement accounts for a large share of the 230 million major operations carried out each year worldwide. Each year in England and Wales alone there are about 180 000 hip and knee replacements.1 Bleeding is an important complication, and many patients require a blood
Ian Roberts, Katharine Ker
openaire +3 more sources
Trials, 2022 Background The prophylactic administration of tranexamic acid reduces blood loss during procedures at high risk of perioperative bleeding. Several studies in cardiac surgery and orthopedics confirmed this finding.
M. Balik +5 more
doaj +1 more source
Tranexamic acid evidence and controversies: An illustrated review
Research and Practice in Thrombosis and Haemostasis, 2021 Tranexamic acid (TXA) is an antifibrinolytic agent commonly used for the treatment or prevention of bleeding. Indications for TXA are diverse, including heavy menstrual bleeding, trauma, postpartum hemorrhage, traumatic brain injury, and surgical site ...
Nicole Relke +2 more
semanticscholar +1 more source
Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients
Anesthesiology, 2021 Background: With increasing use of tranexamic acid in total hip and knee arthroplasties, safety concerns remain. Using national claims data, this study examined tranexamic acid use in patients with preexisting comorbidities.
J. Poeran +5 more
semanticscholar +1 more source
Use of Tranexamic Acid during Total Endoprosthetic Replacement of the Hip Joint
Общая реаниматология, 2010 Objective: to evaluate the blood-saving activity, efficacy, and safety of tranexamic acid. Subjects and methods. Thirty-seven patients allocated into two groups were enrolled in the study of the efficacy of tranexamic acid as an agent in reducing blood ...
D. D. Selivanov +4 more
doaj +1 more source
Efficiency of Cardiotropic Therapy in Neonatal Infants with Posthypoxic Myocardial Damage
Общая реаниматология, 2011 Objective: to define the optimal tranexamic acid dosage regimen to reduce perioperative blood loss during total endo-prosthetic hip joint replacement (TEHJR). Subjects and methods.
Yu. N. Belova +2 more
doaj +1 more source
Bulletin de la Dialyse à Domicile, 2021 Chronic kidney disease patients experience not only more frequent arterial and venous thrombosis but also hemorrhagic episodes. Tranexamic acid is an anti-fibrinolytic molecule that inhibits plasmin activation.
Elodie Bogner +3 more
doaj +1 more source
Journal of the American Medical Association (JAMA), 2020 Importance Traumatic brain injury (TBI) is the leading cause of death and disability due to trauma. Early administration of tranexamic acid may benefit patients with TBI.
Susan E. Rowell +46 more
semanticscholar +1 more source