Cascading cis-cleavage on transcript from trans-acting siRNA-producing locus 3. [PDF]
Int J Mol Sci, 2013 The production of small RNAs (sRNAs) from phased positions set by microRNA-directed cleavage of trans-acting-siRNA-producing locus (TAS) transcript has been characterized extensively; however, the production of sRNAs from non-phased positions remains ...
Zhang C, Li G, Wang J, Zhu S, Li H.
europepmc +7 more sources
Predicted Trans-Acting siRNAs in the Human Brain [PDF]
International Journal of Molecular Sciences, 2015 Endogenous small non-coding RNAs play pivotal roles in regulating gene expression in eukaryotes. Many studies have investigated the function and molecular mechanism of microRNAs in the development and disease of various organisms via mRNA repression of ...
Xiaoshuang Liu +3 more
semanticscholar +5 more sources
Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis [PDF]
Development, 2006 Mutations in the ARGONAUTE gene ZIPPY(ZIP)/AGO7 in Arabidopsis accelerate the juvenile-to-adult transition. A screen for mutations that suppress this precocious phenotype yielded alleles of two auxin-related transcription factors known to be upregulated ...
Christine Hunter +5 more
semanticscholar +4 more sources
Specification of Leaf Polarity in Arabidopsis via the trans-Acting siRNA Pathway [PDF]
Current Biology, 2006 Plants leaves develop proximodistal, dorsoventral (adaxial-abaxial), and mediolateral patterns following initiation. The Myb domain gene PHANTASTICA (PHAN) is required for adaxial fate in many plants , but the Arabidopsis ortholog ASYMMETRIC LEAVES1 (AS1) has milder effects, suggesting that alternate or redundant pathways exist .
Damien Garcia +3 more
semanticscholar +4 more sources
Specificity of ARGONAUTE7-miR390 Interaction and Dual Functionality in TAS3 Trans-Acting siRNA Formation [PDF]
Cell, 2008 Trans-acting siRNA form through a refined RNAi mechanism in plants. miRNA-guided cleavage triggers entry of precursor transcripts into an RNA-DEPENDENT RNA POLYMERASE6 pathway, and sets the register for phased tasiRNA formation by DICER-LIKE4. Here, we show that miR390-ARGONAUTE7 complexes function in distinct cleavage or noncleavage modes at two ...
Taiowa A. Montgomery +9 more
semanticscholar +4 more sources
The CaMV transactivator/viroplasmin interferes with RDR6-dependent trans-acting and secondary siRNA pathways in Arabidopsis [PDF]
Nucleic Acids Research, 2008 Several RNA silencing pathways in plants restrict viral infections and are suppressed by distinct viral proteins. Here we show that the endogenous trans-acting (ta)siRNA pathway, which depends on Dicer-like (DCL) 4 and RNA-dependent RNA polymerase (RDR ...
P. V. Shivaprasad +6 more
semanticscholar +6 more sources
Simple gene silencing using the trans-acting siRNA pathway. [PDF]
Plant Biotechnol J, 2016 SummaryIn plants, particular micro‐RNAs (miRNAs) induce the production of a class of small interfering RNAs (siRNA) called trans‐acting siRNA (ta‐siRNA) that lead to gene silencing. A single miRNA target is sufficient for the production of ta‐siRNAs, which target can be incorporated into a vector to induce the production of siRNAs, and ultimately gene ...
Jacobs TB +4 more
europepmc +5 more sources
Small RNAs mediate transgenerational inheritance of genome-wide trans-acting epialleles in maize
Genome Biology, 2022 Background Hybridization and backcrossing are commonly used in animal and plant breeding to induce heritable variation including epigenetic changes such as paramutation.
Shuai Cao +8 more
doaj +3 more sources
Genome-wide analysis of leafbladeless1-regulated and phased small RNAs underscores the importance of the TAS3 ta-siRNA pathway to maize development. [PDF]
PLoS Genetics, 2014 Maize leafbladeless1 (lbl1) encodes a key component in the trans-acting short-interfering RNA (ta-siRNA) biogenesis pathway. Correlated with a great diversity in ta-siRNAs and the targets they regulate, the phenotypes conditioned by mutants perturbing ...
Marcela C Dotto +5 more
doaj +2 more sources
Biogenesis of <i>trans</i>-acting siRNAs, endogenous secondary siRNAs in plants
Genes & Genetic Systems, 2013 Trans-acting small interfering RNAs (tasiRNAs) are plant-specific endogenous siRNAs that control non-identical mRNAs via cleavage. The production of tasiRNAs is triggered by cleavage of capped and polyadenylated primary TAS transcripts (pri-TASs) by ...
Manabu Yoshikawa
openalex +3 more sources