Results 161 to 170 of about 30,445 (234)

Overexpressed Palladin Rescues Enteropathogenic E. coli (EPEC) Pedestal Lengths in ArpC2 Depleted Cells

Cytoskeleton, Volume 82, Issue 8, Page 497-512, August 2025.
ABSTRACT Enteropathogenic Escherichia coli (EPEC) causes diarrheal disease. Once ingested, these extracellular pathogens attach to the intestinal epithelial cells of their host, collapse the localized microvilli, and generate actin‐rich structures within the host cells that are located beneath the attached bacteria, called “pedestals.” Palladin is an ...
Kaitlin M. Bruzzini, S. Tara Mann, Julian A. Guttman   +2 more
wiley   +1 more source

Blocking YAP1-Liprin-β2 interaction impedes metastasis and promotes tumor suppression in head and neck squamous carcinoma. [PDF]

Sci Rep
Woo SR, Noh JK, Lee MK, Kong M, Min S, Sung JY, Na K, Kang S, Hur JK, Ko SG, Eun YG.   +10 more
europepmc   +1 more source

The role of long non‐coding RNAs in lung cancer metastasis: Molecular mechanisms, pathogenesis and clinical implications

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
LncRNAs are localized in cytosol, nucleus, other sub‐nuclear compartments, and exosomes in the cell, and play significant role in lung cancer dissemination based on their localizations. LncRNAs have emerged as promising biomarkers for both early detection and prognosis.
Musaffe Tuna, Gordon B Mills, Christopher I. Amos   +2 more
wiley   +1 more source

MIAT promotes tumor-infiltrating CD8⁺ T-cell exhaustion and malignant progression of renal cell carcinoma via activating JAK3/STAT3 pathway. [PDF]

J Immunother Cancer
Zhang MX, Jing LY, Tan HT, Dai ZR, Long DZ, Liu HC, Yu AZ, Wang B, Chen ZY, Luo JH, Chen ZH, Wang JF.   +11 more
europepmc   +1 more source

CD31 regulates metabolic switch in Treg migration attenuates rheumatoid arthritis

Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.
This study elucidates metabolic reprogramming in CD31 Tregs during rheumatoid arthritis progression. CD31 Y663F‐mutant Tregs exhibit a glucose‐to‐fructose metabolic shift, characterised by reduced glucose uptake and enhanced fructose utilisation regulated by PFKFB3.
Meijun Liu, Wengqiong Huang, Xiaoli Chen, Zongzhen Meng, Jiawen Yang, Loiola Rodrigo Azevedo, Xiaojiao Zheng, Hao Shen, Wei Jia, Aiping Lyu, Kenneth CP Cheung   +10 more
wiley   +1 more source

Genetic modulation of protein expression in rat brain. [PDF]

iScience
Li L, Wu Z, Guarracino A, Villani F, Kong D, Mancieri A, Zhang A, Saba L, Chen H, Brozka H, Vales K, Senko AN, Kempermann G, Stuchlik A, Pravenec M, Lechner J, Prins P, Mathur R, Lu L, Yang K, Peng J, Williams RW, Wang X.   +22 more
europepmc   +1 more source

Anticancer Molecular Mechanisms of Epigallocatechin Gallate: An Updated Review on Clinical Trials

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Epigallocatechin gallate (EGCG), a bioactive compound abundantly exists in green tea and grapes with strong antioxidant activity and anticancer potential is a suitable approach to reduce the cancer burden. The invitro and invivo anticancer studies of EGCG proved anticancer and anti‐tumor effect through modulation of cancer signaling pathways, reduction
Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Aimen Mazhar, Iqra Baig, Jawaria Javaid, Muzzamal Hussain, Muhammad Imran, Suliman A. Alsagaby, Waleed Al Abdulmonem, Ahmed Mujtaba, Tadesse Fenta Yehuala, Mohammed M. Ghoneim, Ehab M. Mostafa, Mohamed A. Abdelgawad   +13 more
wiley   +1 more source

SRSF6 and SRSF1 coordinately enhance the inclusion of human <i>MUSK</i> exon 10 to generate a Wnt-sensitive MuSK isoform. [PDF]

NAR Mol Med
Nasrin F, Nagar P, Islam MR, Heeamoni SA, Hasan MM, Ohno K, Rahman MA.   +6 more
europepmc   +1 more source

Inhibitors of Tax1‐PDZ Interactions Block HTLV‐1 Viral Transmission by Changing EV Composition

Journal of Extracellular Vesicles, Volume 14, Issue 8, August 2025.
ABSTRACT Extracellular vesicles (EVs) are known to facilitate infection by enveloped RNA viruses including the Human T‐cell leukemia virus type‐1 (HTLV‐1). HTLV‐1‐encoded proteins, like the transactivator and oncoprotein Tax‐1, are loaded into EVs but their precise impact on EV cargos is not yet known.
Jedidja Puttemans, Yasmine Brammerloo, Karim Blibek, Jeremy Blavier, Thandokuhle Ntombela, Inge Van Molle, Julie Joseph, Julien Olivet, Deeya Saha, Manon Degey, Malik Hamaidia, Pooja Jain, Piel Geraldine, Pascale Zimmermann, Dae‐Kyum Kim, Dominique Baiwir, Makon‐Sébastien Njock, Franck Dequiedt, Kourosh Salehi‐Ashtiani, Steven Ballet, Alexander N. Volkov, Jean‐Claude Twizere, Sibusiso B. Maseko   +22 more
wiley   +1 more source

Transgenerational Transmission of Epigenetic Marks During Reproduction in <i>Arabidopsis</i>. [PDF]

Yale J Biol Med
Cheong JJ.
europepmc   +1 more source