Results 191 to 200 of about 46,086 (263)

Vasopressin-Sensitive Aqp2 Regulation Mediated by the TAZ-NR4A1 Axis in Renal Collecting Duct Cells. [PDF]

FASEB J
Choi HS, Jang HJ, Kim WY, Park SA, Park E, Jung HJ, Kwon TH.   +6 more
europepmc   +1 more source

Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA

Advanced Science, Volume 12, Issue 37, October 6, 2025.
Venous thromboembolism (VTE) is a major threat to cancer patients. Cancer‐derived large extracellular vesicles deliver CYBA (p22phox) to neutrophils, triggering reactive oxygen species (ROS) and citrullinated histone H3 (citH3) formation. This drives neutrophil extracellular traps formation (NETosis), elevating VTE risk.
Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Min   +8 more
wiley   +1 more source

Small Interfering RNAs as Critical Regulators of Plant Life Process: New Perspectives on Regulating the Transcriptomic Machinery. [PDF]

Int J Mol Sci
Puchta-Jasińska M, Bolc P, Pietrusińska-Radzio A, Motor A, Boczkowska M.   +4 more
europepmc   +1 more source

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, Volume 12, Issue 38, October 13, 2025.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Fifteen Years of PNPLA3: Transforming Hepatology Through Human Genetics. [PDF]

Liver Int
Romeo S, Valenti L.
europepmc   +1 more source

Epigenome Modifying Tools In Asthma [PDF]

, 2015
Adcock,, Brook, PO, Durham, AL, Perry, M
core   +1 more source

The Novel MuRF2 Target SNX5 Regulates PKA Activity Through Stabilization of RI‐α and Controls Myogenic Differentiation

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Muscle RING finger (MuRF) proteins are striated muscle‐specific E3 ubiquitin ligases essential for muscle homeostasis. Whereas MuRF1 is well known for its role in muscle atrophy, MuRF2 and MuRF3 contribute to microtubule stabilization, influencing muscle differentiation and function.
Ning Li, Jida Hamati, Yi Li, Björn Brinschwitz, Mohamed Ghait, Elisa Martin, Dörte Lodka, Elke Hammer, Britta Fielitz, Uwe Völker, Gunnar Dittmar, Thomas Sommer, Friedrich C. Luft, Jens Fielitz   +13 more
wiley   +1 more source

CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer. [PDF]

Cell Rep
Xiang RR, Lee SA, Tyndall CF, Bhatia AR, Yin J, Singler C, Hauk BJ, Kipp MP, Takeda DY.   +8 more
europepmc   +1 more source

Diabetic Wound Repair: From Mechanism to Therapeutic Opportunities

MedComm, Volume 6, Issue 10, October 2025.
Diabetic wound healing is compromised by chronic metabolic dysfunction that disrupts essential cellular processes. This review examines key predisposing factors, including neuropathy and vascular disease, characterizes dysfunction in critical cell types such as macrophages and fibroblasts, evaluates limitations of current models, compares established ...
Renyuan Wang, Song Gu, Young Hwa Kim, Aejin Lee, Haodong Lin, Dongsheng Jiang   +5 more
wiley   +1 more source

pH-responsive 2D niobium carbide nanosheets for targeted circPUM1 siRNA delivery in ovarian cancer therapy. [PDF]

Mater Today Bio
Guan X, Wang LL, Yang Z, Wang Y, Zhao Y, Wang D.   +5 more
europepmc   +1 more source