Results 21 to 30 of about 30,445 (234)

Ancient trans-Acting siRNAs Confer Robustness and Sensitivity onto the Auxin Response [PDF]

Developmental Cell, 2016
ABSTRACTNovel developmental programs often evolve via cooption of existing genetic networks. To understand this process, we explored cooption of theTAS3tasiRNA pathway in the mossPhyscomitrella patens. We find an ancestral function for this repeatedly redeployed pathway in the spatial regulation of a conserved set of Auxin Response Factors.
Yevgeniy Plavskin, Akitomo Nagashima, Pierre‐François Perroud, Mitsuyasu Hasebe, Ralph S. Quatrano, Gurinder S. Atwal, Marja C.P. Timmermans   +6 more
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MicroRNAs as master regulators of the plant NB-LRR defense gene family via the production of phased, trans-acting siRNAs [PDF]

Genes & Development, 2011
Legumes and many nonleguminous plants enter symbiotic interactions with microbes, and it is poorly understood how host plants respond to promote beneficial, symbiotic microbial interactions while suppressing those that are deleterious or pathogenic. Trans-acting siRNAs (tasiRNAs) negatively regulate target transcripts and are characterized by siRNAs ...
Jixian Zhai, Dong‐Hoon Jeong, Emanuele De Paoli, Sunhee Park, Benjamin D. Rosen, Yupeng Li, Álvaro González, Zhe Yan, S.L. Kitto, Michael A. Grusak, Scott A. Jackson, Gary Stacey, Douglas R. Cook, Pamela J. Green, D. Janine Sherrier, Blake C. Meyers   +15 more
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Expression and processing of polycistronic artificial microRNAs and trans‐acting siRNAs from transiently introduced transgenes in Solanum lycopersicum and Nicotiana benthamiana

The Plant Journal, 2021
SUMMARYTargeted gene silencing using small regulatory RNAs is a widely used technique for genetic studies in plants. Artificial microRNAs are one common approach, as they have the advantage of producing just a single functional small RNA, which can be designed for high target specificity and low off‐target effects.
Alice Lunardon, Samwel Muiruri, Michael J. Axtell   +2 more
openalex   +5 more sources

Assorted Processing of Synthetic Trans-Acting siRNAs and Its Activity in Antiviral Resistance

PLOS ONE, 2015
The use of syn-tasiRNAs has been proposed as an RNA interference technique alternative to those previously described: hairpin based, virus induced gene silencing or artificial miRNAs. In this study we engineered the TAS1c locus to impair Plum pox virus (PPV) infection by replacing the five native siRNAs with two 210-bp fragments from the CP and the 3 ...
Mingmin Zhao, David San León, Frida Mesel, Juan Antonio Garcı́a, Carmen Simón‐Mateo   +4 more
openalex   +6 more sources

Identification of novel drought-responsive microRNAs and trans-acting siRNAs from Sorghum bicolor (L.) Moench by high-throughput sequencing analysis [PDF]

Frontiers in Plant Science, 2015
Small non-coding RNAs (sRNAs) namely microRNAs (miRNAs) and trans-acting small interfering RNAs (tasi-RNAs) play a crucial role in post-transcriptional regulation of gene expression and thus the control plant development and stress responses. In order to identify drought-responsive miRNAs and tasi-RNAs in sorghum, we constructed small RNA libraries ...
Amit Katiyar, Shuchi Smita, Senthilkumar Muthusamy, Viswanathan Chinnusamy, Dev Mani Pandey, K. C. Bansal   +5 more
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Identification of trans‐acting siRNAs in moss and an RNA‐dependent RNA polymerase required for their biogenesis [PDF]

The Plant Journal, 2006
Summary Trans‐acting small interfering RNAs (tasiRNAs) are a class of higher‐plant endogenous siRNAs that, like miRNAs, direct the cleavage of non‐identical transcripts. tasiRNAs derive from non‐coding transcripts (TAS) that are converted into dsRNA by a RNA‐dependent RNA polymerase (RDR6), following their initial miRNA‐guided cleavage.
Mali Talmor‐Neiman, Ran Stav, Liron Klipcan, Kobi Buxdorf, David C. Baulcombe, Tzahi Arazi   +5 more
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Faculty Opinions recommendation of Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2006
Craig S. Pikaard
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SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis [PDF]

Genes & Development, 2004
Higher plants undergo a transition from a juvenile to an adult phase of vegetative development prior to flowering. Screens for mutants that undergo this transition precociously produced alleles of two genes required for posttranscriptional gene silencing (PTGS)—SUPPRESSOR OF GENE SILENCING3 (SGS3) and SUPPRESSOR OF GENE SILENCING2(SGS2)/SILENCING ...
Angela Peragine, Manabu Yoshikawa, Gang Wu, Heidi L. Albrecht, R. Scott Poethig   +4 more
openalex   +4 more sources

DICER-LIKE1 processedtrans-actingsiRNAs mediate DNA methylation [PDF]

Plant Signaling & Behavior, 2013
Small non-coding RNAs (sRNAs) emerge as exquisite molecules that are guided for transcriptional and posttranscriptional gene regulation in eukaryotes. As one class of most important sRNAs in plants, trans-acting small interfering RNAs (ta-siRNAs) initiate from microRNA (miRNA) - mediated cleavage of TAS gene transcripts and subsequently are stabilized ...
Liang Wu
openalex   +4 more sources

Intersection of small RNA pathways in Arabidopsis thaliana sub-nuclear domains. [PDF]

PLoS ONE, 2013
In Arabidopsis thaliana, functionally diverse small RNA (smRNA) pathways bring about decreased RNA accumulation of target genes via several different mechanisms.
Olga Pontes, Alexa Vitins, Thomas S Ream, Evelyn Hong, Craig S Pikaard, Pedro Costa-Nunes   +5 more
doaj   +1 more source