Synergistic effect of split DNA activators of Cas12a with exon-unwinding and induced targeting effect. [PDF]
Huang S, Lou Y, Zheng L.
europepmc +1 more source
Targeting of promoters for trans activation by a carboxy-terminal domain of the NS-1 protein of the parvovirus minute virus of mice [PDF]
Daniel Legendre, Jean Rommelaere
openalex +1 more source
A reconfigurable microneedle electrode array integrated system is developed for minimally invasive and transdermal monitoring of subcutaneous electromyography, reactive oxygen species, and pH values. By assembling discrete thumbtack‐shaped microneedles into an array, the system enables multi‐parameter detection with single‐microneedle resolution.
Zhengjie Liu+12 more
wiley +1 more source
Molecular insights and rational engineering of a compact CRISPR-Cas effector Cas12h1 with a broad-spectrum PAM. [PDF]
Zheng W+9 more
europepmc +1 more source
DNA-binding and trans-activation properties of Drosophila E2F and DP proteins.
Brian David Dynlacht+4 more
openalex +1 more source
Functional analysis of interactions between Tat and the trans-activation response element of human immunodeficiency virus type 1 in cells [PDF]
Ying Luo+4 more
openalex +1 more source
Electrical Microneedles for Wound Treatment
A review on state‐of‐art research concerning electrical microneedles applied for wound treatment is presented. After a comprehensive analysis of mechanisms of electrical stimulation on wound healing, the derived three types of electrical microneedles are clarified and summarized. Further, their applications in wound healing are highlighted.
Yu Wang+6 more
wiley +1 more source
Ultrasensitive detection of clinical pathogens through a target-amplification-free collateral-cleavage-enhancing CRISPR-CasΦ tool. [PDF]
Chen H+20 more
europepmc +1 more source
Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment
A novel orally drug‐probiotic co‐delivery system designated as Rh‐YBS for UC treatment, which highlights three innovations: (i) YPs involves colonic submucosa delivery via M cells; (ii) Rh (drug) promotes the colonization and growth of BS (probiotic) in the colon.
Lingqiang Li+21 more
wiley +1 more source