Results 291 to 300 of about 3,929,670 (363)

A Dual‐Targeting T6SS DNase Drives Bacterial Antagonism and Eukaryotic Apoptosis via the cGAS‐STING‐TNF Axis

Advanced Science, EarlyView.
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song, Lei Xu, Pengfei Zhang, Shuying Li, Yichen Qu, Yixin Zhao, Zhenkun Shi, Ruiqi Ma, Yongdong Li, Yi Chen, Yao Wang, Zhengfan Jiang, Gehong Wei, Xihui Shen   +13 more
wiley   +1 more source

A High-Fat Diet Induces Epigenetic 1-Carbon Metabolism, Homocystinuria, and Renal-Dependent HFpEF. [PDF]

Nutrients
Tyagi SC.
europepmc   +1 more source

Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label

Advanced Science, EarlyView.
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong, Xiaohui Wang, Jintao Yu, Li Wen, Chengwen Zheng, Ge Yin, Kai Xu, Weiwei He, Hao Wang, Xiaoli Lan, Dawei Jiang, Yu Sun   +11 more
wiley   +1 more source

Stereoselective Synthesis of (<i>R</i>)-all-<i>trans</i>-13,14-Dihydroretinol and -Retinoic Acid. [PDF]

J Org Chem
Wienecke P, Minnaard AJ.
europepmc   +1 more source

Trans-activator Tax of Human T-Cell Leukemia Virus Type 1 Enhances Mutation Frequency of the Cellular Genome

, 1999
Hiroshi Miyake, Takeshi Suzuki, Hiroshi Hirai, Mitsuaki Yoshida   +3 more
openalex   +1 more source

Macroscopic Structural Transition of Nickel Dithiolate Capsule with Uniaxial Magnetic Anisotropy in Water

Advanced Science, EarlyView.
An amphiphilic open‐shell d/π‐conjugated nickel dithiolate salt forms a bilayer capsule exhibiting uniaxial magnetic anisotropy, driven by spin–spin interactions. The capsule, exceptionally stable in aqueous environments, undergoes temperature‐dependent structural transitions representing, to the knowledge, the first observation of such behavior for ...
Tomoko Fujino, Mafumi Hishida, Masatoshi Ito, Toshikazu Nakamura, Mizue Asada, Naoya Kurahashi, Hisao Kiuchi, Yoshihisa Harada, Koji Harano, Rie Makiura, Kanokwan Jumtee Takeno, So Yokomori, Hiroshi Oike, Hatsumi Mori   +13 more
wiley   +1 more source

The CRISPR-Cas13a Gemini System for noncontiguous target RNA activation. [PDF]

Nat Commun
Zhao H, Sheng Y, Zhang T, Zhou S, Zhu Y, Qian F, Liu M, Xu W, Zhang D, Hu J.   +9 more
europepmc   +1 more source

A trans-acting peptide activates the yeast a1 repressor by raising its DNA-binding affinity

, 1999
Martha R. Stark, Dominik Escher, Alexander D. Johnson   +2 more
openalex   +2 more sources

Impact of Disorder, Porosity, and Surface Chemistry of Salt Templated Carbons on Capacitance

Advanced Science, EarlyView.
Soft‐salt templating method allowed to obtain a series of tailored porous carbons for EDLCs. Neutral aqueous electrolytes enabled to reach 1.6 V. Linear dependence of ID/IG ratio vs. capacitance values has been proven. Active surface area related to carbon defects supported the Raman findings.
Amelia Klimek, Bénédicte Réty, Camélia Matei Ghimbeu, Elzbieta Frackowiak   +3 more
wiley   +1 more source

Systemic acquired resistance inducing chemicals mitigate black scurf disease in potato by activating defense-related enzymes. [PDF]

PeerJ
Buswal MK, Punia R, Kumar M, Tiwari RK, Lal MK, Kumar R.   +5 more
europepmc   +1 more source