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Indigeneity and ‘authenticity’ in African trans* activism
Sexualities, 2020Most efforts to promote gender equity in sub-Saharan Africa have been rooted in a Western heteronormative framework inherited from colonialism that aims at ‘balancing’ gender rather than deconstructing it. Dismantling this entrenched, though exogenous, binary is a daunting task, especially since, over time, it has become widely accepted as ...
Katlego Kolanyane-Kesupile +1 more
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Insertion specificity and trans-activation of IS801
Molecular and General Genetics MGG, 1998The transposable element IS801, isolated from plasmid pMMC7105 of Pseudomonas syringae pv. phaseolicola, transposes in Escherichia coli to plasmid targets, expressing a relatively relaxed target specificity. The target sequences are tetramers with homology with the left terminus (GAAC) of the transposing unit, the alternative targets being GAAC, GGAC ...
Martin Romantschuk +3 more
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Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators.
Human Gene Therapy, 2002The tetracycline (Tet)-dependent regulatory system has been widely used for controlling gene expression. The Tet-on version of the system, in which the reverse Tet-responsive transcriptional activator (rtTA) is positively regulated by Tet or its analogs,
S. Lamartina +9 more
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Lost in Transition?Digital trans activism on Youtube
Information, Communication & Society, 2020This article intends to contribute to a novel research area - the construction of critical transgender narratives on Youtube – examining how some Spanish trans youtubers shift the focus from the ‘fleshy metamorphosis’ [Barnett, J. T. (2015). Fleshy metamorphosis: Temporal pedagogies of transsexual counterpublics. In L. G. Spencer & J. C. Capuzza (Eds.),
Iolanda Tortajada +3 more
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Cytomegalovirus as a trans-activator of cellular genes
Seminars in Virology, 1994Abstract Cytomegalovirus proteins have been shown to act as trans-activators on other, heterologous, viral promoters as well as on its own promoter. In the immunocompromised host, part of the response to cytomegalovirus infection may be related to the effect of viral proteins on the transcription of cellular genes.
Gary W. Hunninghake, Lois J. Geist
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Translational regulation of GCN4 and the general amino acid control of yeast.
Annual Review of Microbiology, 2005Cells reprogram gene expression in response to environmental changes by mobilizing transcriptional activators. The activator protein Gcn4 of the yeast Saccharomyces cerevisiae is regulated by an intricate translational control mechanism, which is the ...
A. Hinnebusch
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Signaling by Receptor Tyrosine Kinases
, 1993The epidermal growth factor receptor (EGFR) is one member of the ERBB family of transmembrane gly-coprotein tyrosine receptor kinases (RTK). Binding of EGFR to its ligands induces conformational change that unmasks the dimerization interface in the ...
Joseph Schlessinger, M. Lemmon
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Perspectives on the autocrine and paracrine functions of trans-activating factors
Restorative Neurology and Neuroscience, 1993It is a more and more widespread observation that growth factors can, on occasion, be found within nuclei where they may serve as trans-activating factors. This dual action raises the possibility that, on their side, trans-activating factors might be secreted and act both at the membrane and at the nuclear level of target cells. At the same time it has
Alain Prochiantz +2 more
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Purification and biochemical characterization of the promoter-specific transcription factor, Sp1.
Science, 1986The biochemical analysis of cellular trans-activators involved in promoter recognition provides an important step toward understanding the mechanisms of gene expression in animal cells.
M. Briggs +3 more
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Cis- and Trans-Activation of HIV
1989Human immunodeficiency virus (HIV) is the causative agent of acquired immunodeficiency syndrome (AIDS). Infection via cell-free virus particles is restricted to CD4-positive cells, including macrophages, helper T — cells, and glial cells. In contrast to the specificity of binding to the cell surface receptor, HIV LTR-directed gene expression is carried
Flossie Wong-Staal, Jay Rappaport
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