Results 341 to 350 of about 3,929,670 (363)
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New insights into the mechanism of HIV-1 trans-activation
Trends in Genetics, 1992acting factors were found sub- sequently in all other lentiviruses, including HIV-2 and simian im- munodeficiency virus (SIV). These findings stimulated intensive re- search into the mechanism of action of Tat and a search for antiviral compounds 1. Now, nearly seven years later, a coherent pic- ture of how Tat works is emerging. Transcription from the
Jonathan Karn, Maria A. Graeble
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A yeast chromosomal origin of DNA replication defined by multiple functional elements.
Science, 1992Although it has been demonstrated that discrete origins of DNA replication exist in eukaryotic cellular chromosomes, the detailed organization of a eukaryotic cellular origin remains to be determined. Linker substitution mutations were constructed across
Y. Marahrens +3 more
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The (In)Visible T: Trans Activism in Croatia (2004–2014)
2016This chapter provides an account of the development of trans activism in Croatia between 2004 and 2014. The authors trace previous and recent activities and organisations to show how transphobia within some parts of the LGBT (activist) “community” has forced trans activism to evolve from the practically invisible T inside the LGBT initiatives, via ...
J. Poštić +2 more
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A cytosolic trans-activation domain essential for ammonium uptake
Nature, 2007Polytopic membrane proteins are essential for cellular uptake and release of nutrients. To prevent toxic accumulation, rapid shut-off mechanisms are required. Here we show that the soluble cytosolic carboxy terminus of an oligomeric ammonium transporter from Arabidopsis thaliana serves as an allosteric regulator essential for function; mutations in the
Wolf B. Frommer +4 more
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Transcriptional trans-activating function of hepatitis B virus
Journal of Virology, 1987The ability of hepatitis B virus (HBV) to stimulate the expression of a cellular gene was investigated by using a transient-expression system. A plasmid in which the expression of the bacterial chloramphenicol acetyltransferase (cat) gene had been placed under the control of the DNA sequences that regulate the expression of the human beta-interferon ...
Jr-Shin Twu, R. H. Schloemer
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Amyloid formation by intrinsically disordered trans-activation domain of cMyb
Biochemical and Biophysical Research Communications, 2020The cMyb trans-activation domain is one of the model systems to understand the folding and binding mechanisms in intrinsically disordered proteins. cMyb (291-315) TAD (cMyb TAD) upon interaction with KIX plays a crucial role in transcriptional regulation.
Rajanish Giri, Kundlik Gadhave
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AIDS virus: More and better trans-activation
Nature, 1986SCOPUS: ar.j ; info:eu-repo/semantics ...
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Virology, 1992
The parvovirus H-1 P38 promoter contains a trans-activation responsive element (tar). It was previously shown that the parvovirus H-1 nonstructural protein NS1 positively regulates the expression of the P38 promoter for the viral capsid protein gene via the tar (Rhode and Richard, 1987, J. Virol. 61, 2807-2515).
Mi-Li Gu, Solon L. Rhode
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The parvovirus H-1 P38 promoter contains a trans-activation responsive element (tar). It was previously shown that the parvovirus H-1 nonstructural protein NS1 positively regulates the expression of the P38 promoter for the viral capsid protein gene via the tar (Rhode and Richard, 1987, J. Virol. 61, 2807-2515).
Mi-Li Gu, Solon L. Rhode
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Mechanisms of Viral-Mediated Trans-Activation of Transcription
1989Publisher Summary This chapter discusses the features and characteristics of the E1A trans-activation system besides the related details deriving from other relevant viral systems. The studies of herpes virus trans-activation have provided many details both unique and similar to the E1A system.
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Role of Cjun in Gγ-Globin Gene Trans-Activation.
Blood, 2008Abstract Previous studies from our laboratory demonstrated the role of the G-CRE (Gγ-globin cAMP response element) in drug-mediated fetal hemoglobin induction. The G-CRE located at −1222 to −1229 in the promoter of Gγ-globin gene, contains binding site for trans-factors CREB1, ATF-2 and cJun.
Betty S. Pace +5 more
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