Results 141 to 150 of about 118,138 (256)

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

Rethinking nutritional villains: A trans-fatty acid identified to boost immunotherapy. [PDF]

Clin Transl Med
Fan H, Zhang FQ, Chen J.
europepmc   +1 more source

A trans-fatty acid-rich diet promotes liver tumorigenesis in HCV core gene transgenic mice. [PDF]

Carcinogenesis, 2020
Hu X, Wang X, Jia F, Tanaka N, Kimura T, Nakajima T, Sato Y, Moriya K, Koike K, Gonzalez FJ, Nakayama J, Aoyama T.   +11 more
europepmc   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Blood biomarkers of trans-fatty acid intake among Nigerian adults in the Federal Capital Territory: a cross-sectional study. [PDF]

Am J Clin Nutr
Marklund M, Billyrose S, Orji IA, Ikechukwu-Orji MU, Okoro C, Obagha C, Iyer G, Jamro EL, Ojo A, Harris WS, Wu JH, Hirschhorn LR, Van Horn L, Huffman MD, Ojji DB.   +14 more
europepmc   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino, Christopher R. Friesen, Geoffrey E. Hill, Dalton C. Leibold, Pablo Recio, Karine Salin, Kristoffer H. Wild, Daniel W.A. Noble   +7 more
wiley   +1 more source

Effects of a High Trans Fatty Acid Diet on Kidney-, Liver-, and Heart-Associated Diseases in a Rabbit Model. [PDF]

Metabolites
Ismail H, Mubashar Z, Khan H, Naveed Z, Dilshad E, Bhatti MZ, Anwaar S, Saleem S, Mehmood S, Rahman A, Rashid U, Fouad D, De Waard M, Batiha GE.   +13 more
europepmc   +1 more source

Plasma Trans Fatty Acid Levels, Cardiovascular Risk Factors and Lifestyle: Results from the Akershus Cardiac Examination 1950 Study. [PDF]

Nutrients, 2020
Chandra A, Lyngbakken MN, Eide IA, Røsjø H, Vigen T, Ihle-Hansen H, Orstad EB, Rønning OM, Berge T, Schmidt EB, Tveit A, Omland T, Svensson M.   +12 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Association of plasma trans fatty acid concentrations with blood pressure and hypertension in U.S. adults. [PDF]

Front Endocrinol (Lausanne)
Luan M, Tian Y, Yan D, Liang S.
europepmc   +1 more source