Results 161 to 170 of about 3,641,959 (223)

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, EarlyView.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Synergistic anticancer effects of peanut hairy root culture crude extract in combination with gemcitabine against cholangiocarcinoma. [PDF]

Sci Rep
Wongkham W, Wongkham P, Limmongkon A, Kaewkong W, Kumphune S, Phimsen S.   +5 more
europepmc   +1 more source

A Melanoma Transplanted in Nude Mice Has Both Host‐ and Tumor‐Derived Blood Vessel‐ and Nerve‐Like Structures

Cancer Science, EarlyView.
Nestin‐driven green fluorescent protein (ND‐GFP) expressing peripheral blood vessels and nerves in the subcutaneous tissue of the ND‐GFP mice extended into the transplanted melanoma such that ND‐GFP was enhanced at the margin of the melanoma compared to the tumor‐free side.
Koya Obara, Azusa Sasaki, Yuko Hamada, Yutaro Kubota, Yusuke Aoki, Noriyuki Masaki, Michael Bouvet, Yasuyuki Amoh, Robert M. Hoffman   +8 more
wiley   +1 more source

Formulation Attributes and Preclinical Wound Healing Outcomes of Natural Product Based Nanoemulsions: A Systematic Review. [PDF]

Int J Nanomedicine
Afandi F, Firmansyah F, Narsa AC, Wilar G, Mohammed AFA, Mahmoud SA, Wathoni N.   +6 more
europepmc   +1 more source

Potent Anti-adipogenic Activity of Cyclopeptide Mallotumide A on Murine 3T3-L1 Adipocytes. [PDF]

ACS Omega
Laowittawat C, Boonprasert P, Sawektreeratana N, Hongthong S, Reutrakul V, Kuhakarn C, Jitrapakdee S.   +6 more
europepmc   +1 more source

Alpha-Ketoglutarate Attenuates UVB-Induced Skin Photoaging by Restoring Mitochondrial Redox Homeostasis. [PDF]

Antioxidants (Basel)
Zhang W, Zhang Y, Wang X, Chen Y, Li Y, Sun Y.   +5 more
europepmc   +1 more source

PARP1 rewires neuroinflammatory and redox metabolism associated with reactive neuroglia in neuropathic pain. [PDF]

Redox Biol
Denaro S, D'Aprile S, Gervasi A, Russo V, Bellia F, Giallongo S, Lavoro A, Candido S, Braga A, Gourine AV, Li Volti G, Pasquinucci L, Amorini AM, Parenti C, Parenti R, Vicario N.   +15 more
europepmc   +1 more source

Light-Activated RPE65 Inhibitors Enable On-Demand Visual Cycle Control. [PDF]

J Am Chem Soc
Bassetto M, Li B, Chen X, Zhang J, Hu Y, Zaluski J, Brumit LM, Willis PM, Grun F, Palczewski K, Kiser PD, Tochtrop GP.   +11 more
europepmc   +1 more source

InterPLAY: A Framework to Describe Play and STEM Engagement at Exhibits for Young Children

Curator: The Museum Journal, EarlyView.
ABSTRACT Play‐based STEM learning at exhibits is a feature of children's museums and science centers; yet little is known about how these exhibits support young children's STEM engagement. This study developed and tested the interPLAY Framework to describe play‐based STEM engagement at exhibits for young children.
Kelly L. Hoke, Martin Storksdieck, Kelly Riedinger, Jessica J. Luke, Jennifer Rehkamp   +4 more
wiley   +1 more source

Retinol Binding Protein 4 Promotes Chondrocyte and Osteoclast Differentiation. [PDF]

Biology (Basel)
Quincey A, Mohan S, Edderkaoui B.
europepmc   +1 more source