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Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
De Robi a Rubí : la “trans”-formación en “otra” en la novela Soy lo que quieras llamarme
Este trabajo tiene por objetivo estudiar algunos aspectos que suelen aparecer en la producción literaria latinoamericana a partir del año 1994. Nos referimos a la presencia de personajes trans (travestis, transexuales y transgéneros) que se transforman ...
Henri Billard
doaj +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
O DISPOSITIVO JORNALÍSTICO E OS DISCURSOS TRANS: UMA ANÁLISE DA FOLHA DE SÃO PAULO
Este trabalho tem como ojetivo problematizar a produção dos discursos sobre os discursos trans veiculados na mídia brasileira, a partir de uma análise que parte dos debates foucaultianos e das discussões de gênero e transfeminismo hodiernas.
Atílio Butturi Jr. +1 more
doaj +1 more source
Cis, trans: above all, metaphors. Cisjordan, region skirting the Jordan River. Cisplatin, Uruguay’s ancient name, region occupying one of the banks of the Prata River. Trans- Amazonian, that which crosses the Amazon; transatlantic, that which crosses the Atlantic. Cisalpine, transalpine.
openaire +3 more sources
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
USE OF SEWAGE SLUDGE IN SOIL COMPOSITION
Utilization of sewage sludge is the problem of many cities. But the presence of heavy metals in them is the main problem for their use as components of fertilizers and as a part of soil composition.
I. V. Grekhova +3 more
doaj
The work is devoted to the study of the influence of the quality of electrical energy on the service life of electrodes of plasma thermochemical fuel treatment systems used in thermal power plants running on coal fuel.
Viktoria V. Romanova +3 more
doaj +1 more source

