Results 41 to 50 of about 1,762,571 (306)

pvz22/Trans-reg_pleiotropy: Trans-reg_pleiotropy

open access: yes, 2022
Scripts used in "Pleiotropic effects of trans-regulatory mutations on fitness and gene expression." (Vande Zande, Hill, and Wittkopp ...
pvz22
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Comprehensive assessment of factors affecting the operational reliability of low-voltage asynchronous electric motors of a coal mining complex

open access: yesИзвестия высших учебных заведений: Проблемы энергетики
THE RELEVANCE of this study lies in solving the problem of reliable functioning of elements of energy systems and ensuring their effective operation during open-pit mining.
V. V. Romanova   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Trans-itioning lives, trans-forming places

open access: yes, 2023
Trans-itioning lives, trans-forming ...
Merinda Kelly (14287493)   +4 more
core  

Trans Nzoia County Investment Plan 2025/2026 [PDF]

open access: yes
This Investment Plan for the financial year 2025 marks a significant milestone in the journey of Trans Nzoia County to realise its vision of becoming an “agro-industrialised county with high quality of life for residents”.
County Government of Trans Nzoia
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Trans Ecologies Symposium [PDF]

open access: yes, 2023
‘The Shelled Gastropod: Trans-Corporeality In Necro-Ecologies’ was presented as part of the Trans Ecologies Symposium, Department of Geography at Durham University. Abstract: This paper contributes to contemporary dialogues on the permeability of bodies,
Sharples, V.
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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