Results 61 to 70 of about 880,312 (268)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Ciencia Política, 2018 Este conjunto de reflexiones que se presentan bajo la forma de un libro académico son el resultado de un esfuerzo colectivo por establecer un diálogo con una de las (quizás la) pensadoras más conocidas de las teorías queer con las experiencias vitales de
Andrea Barrera
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Trans* / Trans*Geschlechtlichkeit
, 2015 Das Präfix 'trans-' ist aus dem Lateinischen hergeleitet und bedeutet 'jenseits'. Bezogen auf Geschlecht deutet trans* auf Lebensweisen hin, die nicht in einer (vermeintlich natürlichen und angeborenen) Zweigeschlechtlichkeit aufgehen. Transgeschlechtlichkeit wurde in aktivistischen Zusammenhängen in Abgrenzung zu der medizinisch-psychologisch ...
Kleiner, Bettina, Scheunemann, Kim
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FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
GROWTH AND DEVELOPMENT OF ONION AT APPLICATION OF HUMIC PREPARATION
Вестник Кемеровского государственного университета, 2015 Reaction of three onion cultivars to the use of humic growth regulator when soaking the set onion and double watering of plants is established. The preparation Rostok positively affected the biometric indicators of plants, exceeding the control group ...
N. V. Litvinenko +2 more
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
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Matías Máximo, El Nunca Más de las locas: Resistencia y deseo en la última dictadura
Estudios de Teoría Literaria, 2023 Reseña bibliográfica del libro de Matías Máximo, El Nunca Más de las locas. Resistencia y deseo en la última dictadura, Buenos Aires, Marea, 2023.
Martin Villagarcia
doaj
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source