Results 71 to 80 of about 6,251,106 (337)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell Communication and Signaling, 2018 IL-6 classic signaling is linked to anti-inflammatory functions while the trans-signaling is associated with pro-inflammatory responses. Classic signaling is induced via membrane-bound IL-6 receptor (IL-6R) whereas trans-signaling requires prior binding ...
M. M. Zegeye +7 more
semanticscholar +1 more source
Relevance of cis- and trans-dichloride Ru intermediates in Grubbs-II olefin metathesis catalysis (H(2)IMesCl(2)Ru=CHR) [PDF]
, 2008 Using density functional theory with the B3LYP and M06 functionals, we show conclusively that the (H2IMes)(Cl)2Ru olefin metathesis mechanism is bottom-bound with the chlorides remaining trans throughout the reaction, thus attempts to effect diastereo ...
Benitez, Diego +2 more
core +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Costurera, trabajadora sexual y comparsera
Boletín de Arte, 2022 Este artículo busca analizar una obra de la artista trans Patricia Ramirez (Ciudad de Corrientes, 1981) en el marco de los carnavales barriales 2020, donde interpretó como figura de Destaque Adulto a Eva Perón.
Agustina Gálligo Wetzel +1 more
doaj +1 more source
Hepatic stellate cells and parasite-induced liver fibrosis [PDF]
, 2010 : Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Allen, JT +3 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Transitar: cuerpo y resistencia. Una mirada micropolítica a la experiencia trans
Razón Crítica, 2021 La expresión “No hay nada más político que las tetas de una trans” evidencia una politización del cuerpo, un acto de rebeldía y resistencia al transgredir el orden establecido. Este ejercicio es guiado por el relato de una transfeminista, Ana Lu Laferal,
Jhon Fernando Jaramillo Taborda
doaj +1 more source
Tumblr was a trans technology: the meaning, importance, history, and future of trans technologies
Feminist Media Studies, 2019 Building from previous researchers’ conceptions of queer technologies, we consider what it means to be a trans technology. This research study draws from interviews with Tumblr transition bloggers (n = 20), along with virtual ethnography, trans theory ...
Oliver L. Haimson +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source