Results 1 to 10 of about 134,646 (295)

Liver diseases, transaminases, and hepatobiliary–pancreatic cancer risk: a cohort and Mendelian randomisation study using data from UK Biobank [PDF]

BMJ Open Gastroenterology
Objective Liver diseases are established risk factors for hepatobiliary and pancreatic cancers. This study explores the relationship between liver disease and hepatobiliary–pancreatic cancers, focusing on transaminase levels and genetic susceptibility ...
Yuan Yuan, Tingting Li, Yong Jiang, Yuan Chen, Qing Tian, Rufu Chen, Chonghui Hu, Daixin Wu, Huimou Chen, Rihua He, Tianhao Huang, Honghui Jiang, Wentao Zhong, Jiale Jiang, Shangyou Zheng   +14 more
doaj   +2 more sources

Pyridoxamine phosphate transaminase [PDF]

Biochemical Journal, 1957
R. BRIAN BEECHEY, Frank Charles Happold
openalex   +4 more sources

Mechanism of transaminase action [PDF]

Biochemical Journal, 1961
T. Oshima, N. Tamiya
  +7 more sources

Elevated De Ritis Ratio Is Associated With Poor Prognosis in COVID-19: A Systematic Review and Meta-Analysis

Frontiers in Medicine, 2021
Objective: This meta-analysis aims to assess whether elevated De Ritis ratio is associated with poor prognosis in patients with coronavirus 2019 (COVID-19).Methods: A systematic literature search was performed using PubMed, Embase, and EuropePMC ...
Raymond Pranata, Ian Huang, Ian Huang, Michael Anthonius Lim, Emir Yonas, Rachel Vania, Rachel Vania, Antonia Anna Lukito, Antonia Anna Lukito, Sally Aman Nasution, Bambang Budi Siswanto, Raden A. Tuty Kuswardhani   +11 more
doaj   +1 more source

Hydrogel-Based Enzyme and Cofactor Co-Immobilization for Efficient Continuous Transamination in a Microbioreactor

Frontiers in Bioengineering and Biotechnology, 2021
A microbioreactor was developed in which selected amine transaminase was immobilized together with the cofactor pyridoxal phosphate (PLP) to allow efficient continuous transamination. The enzyme and cofactor were retained in a porous copolymeric hydrogel
Tadej Menegatti, Polona Žnidaršič-Plazl, Polona Žnidaršič-Plazl   +2 more
doaj   +1 more source

The Association of COVID-19 Degree on Transamination and Bilirubin Levels of COVID-19 Patients in RSUD Dr. Saiful Anwar Malang

Clinical and Research Journal in Internal Medicine, 2022
Background : Corona virus 2019 (COVID-19) is an infectious viral disease caused by SARS-CoV-2 that has infected the world. COVID-19 can cause abnormalities which are characterized by increased levels of the enzyme transaminase and bilirubin.
Ade Rahmawati, Syifa Mustika
doaj   +1 more source

On the flexibility of the cellular amination network in E coli

eLife, 2022
Ammonium (NH4+) is essential to generate the nitrogenous building blocks of life. It gets assimilated via the canonical biosynthetic routes to glutamate and is further distributed throughout metabolism via a network of transaminases.
Helena Schulz-Mirbach, Alexandra Müller, Tong Wu, Pascal Pfister, Selçuk Aslan, Lennart Schada von Borzyskowski, Tobias J Erb, Arren Bar-Even, Steffen N Lindner   +8 more
doaj   +1 more source

Synthesis of Sitagliptin Intermediate by a Multi-Enzymatic Cascade System Using Lipase and Transaminase With Benzylamine as an Amino Donor

Frontiers in Bioengineering and Biotechnology, 2021
Herein, we report the development of a multi-enzyme cascade using transaminase (TA), esterase, aldehyde reductase (AHR), and formate dehydrogenase (FDH), using benzylamine as an amino donor to synthesize the industrially important compound sitagliptin ...
Taresh P. Khobragade, Sharad Sarak, Amol D. Pagar, Hyunwoo Jeon, Pritam Giri, Hyungdon Yun   +5 more
doaj   +1 more source

Mechanisms of ethanol liver damage in rats with different emotionality

Journal of Education, Health and Sport, 2021
Alcoholic liver disease is associated with liver injury ranging from steatosis to steatohepatitis, fibrosis and cirrhosis. One of the mechanisms of organs damage is cytokines influences. The intensity of injury depends on individual reactivety.The aim of
O. A. Коstiuk, O. V. Denefil
doaj   +1 more source

Dual-function transaminases with hybrid nanoflower for the production of value-added chemicals from biobased levulinic acid

Frontiers in Bioengineering and Biotechnology, 2023
The U.S. Department of Energy has listed levulinic acid (LA) as one of the top 12 compounds derived from biomass. LA has gained much attention owing to its conversion into enantiopure 4-aminopentanoic acid through an amination reaction.
Taresh P. Khobragade, Pritam Giri, Amol D. Pagar, Mahesh D. Patil, Sharad Sarak, Sangwoo Joo, Younghwan Goh, Seohee Jung, Hyunseok Yoon, Subin Yun, Youkyoung Kwon, Hyungdon Yun   +11 more
doaj   +1 more source