Results 1 to 10 of about 251,310 (295)
Rational design of a (S)-selective-transaminase for asymmetric synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine [PDF]
, 2016 Amine transaminases offer an environmentally sustainable synthesis route for the production of pure chiral amines. However, their catalytic efficiency toward bulky ketone substrates is greatly limited by steric hindrance and therefore presents a great ...
Allen, Christopher C.R. +12 more
core +4 more sources
Pyridoxamine phosphate transaminase [PDF]
Biochemical Journal, 1957 R. BRIAN BEECHEY, Frank Charles Happold
openalex +4 more sources
Mechanism of transaminase action [PDF]
Biochemical Journal, 1961 Takeshi Oshima, Nanako Tamiya
openalex +5 more sources
Nutritional Status of Tuberculosis Patients in Against Serum Glutamate Pyruvate Transaminase Levels
Magna Medika, 2021 Background: Treatment of Tuberculosis patients are given in the form of a drugs combination. Some drugs which are Pyrazinamide, Isoniazid and Rifampicin can provide hepatotoxic side effects.
Iqbal Donarika Widagdo +2 more
doaj +1 more source
Frontiers in Medicine, 2021 Objective: This meta-analysis aims to assess whether elevated De Ritis ratio is associated with poor prognosis in patients with coronavirus 2019 (COVID-19).Methods: A systematic literature search was performed using PubMed, Embase, and EuropePMC ...
Raymond Pranata +11 more
doaj +1 more source
Engineering an Amine Transaminase for the Efficient Production of a Chiral Sacubitril Precursor
, 2021 An amine transaminase was engineered for the efficient production of a chiral precursor to sacubitril, (2R,4S)-5-([1,1′-biphenyl]-4-yl)-4-amino-2-methylpentanoic acid, a key component in the blockb...
S. Novick +10 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 A microbioreactor was developed in which selected amine transaminase was immobilized together with the cofactor pyridoxal phosphate (PLP) to allow efficient continuous transamination. The enzyme and cofactor were retained in a porous copolymeric hydrogel
Tadej Menegatti +2 more
doaj +1 more source
Clinical and Research Journal in Internal Medicine, 2022 Background : Corona virus 2019 (COVID-19) is an infectious viral disease caused by SARS-CoV-2 that has infected the world. COVID-19 can cause abnormalities which are characterized by increased levels of the enzyme transaminase and bilirubin.
Ade Rahmawati, Syifa Mustika
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Specificity of transaminase activities in the prediction of drug-induced hepatotoxicity.
Journal of Toxicological Sciences, 2020 The activities of the transaminases (aminotransferases) alanine aminotransferase and aspartate aminotransferase in the blood (serum or plasma) are widely used as sensitive markers of possible tissue damage and, in particular for liver toxicity.
Akio Kobayashi, Yusuke Suzuki, S. Sugai
semanticscholar +1 more source
A dog model for acetaminophen-induced fulminant hepatic failure. [PDF]
, 1989 The development of a large animal model of fulminant hepatic failure produced with acetaminophen that should be useful in the development and evaluation of potential medical therapies for the important clinical problem of fulminant hepatic failure is ...
Barone, M +7 more
core +2 more sources