Results 1 to 10 of about 292,424 (340)
Frontiers in Bioengineering and Biotechnology, 2021 A microbioreactor was developed in which selected amine transaminase was immobilized together with the cofactor pyridoxal phosphate (PLP) to allow efficient continuous transamination. The enzyme and cofactor were retained in a porous copolymeric hydrogel
Tadej Menegatti +2 more
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Frontiers in Medicine, 2021 Objective: This meta-analysis aims to assess whether elevated De Ritis ratio is associated with poor prognosis in patients with coronavirus 2019 (COVID-19).Methods: A systematic literature search was performed using PubMed, Embase, and EuropePMC ...
Raymond Pranata +11 more
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Clinical and Research Journal in Internal Medicine, 2022 Background : Corona virus 2019 (COVID-19) is an infectious viral disease caused by SARS-CoV-2 that has infected the world. COVID-19 can cause abnormalities which are characterized by increased levels of the enzyme transaminase and bilirubin.
Ade Rahmawati, Syifa Mustika
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Nutritional Status of Tuberculosis Patients in Against Serum Glutamate Pyruvate Transaminase Levels
Magna Medika, 2021 Background: Treatment of Tuberculosis patients are given in the form of a drugs combination. Some drugs which are Pyrazinamide, Isoniazid and Rifampicin can provide hepatotoxic side effects.
Iqbal Donarika Widagdo +2 more
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Frontiers in Bioengineering and Biotechnology, 2021 Herein, we report the development of a multi-enzyme cascade using transaminase (TA), esterase, aldehyde reductase (AHR), and formate dehydrogenase (FDH), using benzylamine as an amino donor to synthesize the industrially important compound sitagliptin ...
Taresh P. Khobragade +5 more
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On the flexibility of the cellular amination network in E coli
eLife, 2022 Ammonium (NH4+) is essential to generate the nitrogenous building blocks of life. It gets assimilated via the canonical biosynthetic routes to glutamate and is further distributed throughout metabolism via a network of transaminases.
Helena Schulz-Mirbach +8 more
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Mechanisms of ethanol liver damage in rats with different emotionality
Journal of Education, Health and Sport, 2021 Alcoholic liver disease is associated with liver injury ranging from steatosis to steatohepatitis, fibrosis and cirrhosis. One of the mechanisms of organs damage is cytokines influences. The intensity of injury depends on individual reactivety.The aim of
O. A. Коstiuk, O. V. Denefil
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Frontiers in Bioengineering and Biotechnology, 2023 The U.S. Department of Energy has listed levulinic acid (LA) as one of the top 12 compounds derived from biomass. LA has gained much attention owing to its conversion into enantiopure 4-aminopentanoic acid through an amination reaction.
Taresh P. Khobragade +11 more
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Rational design of a (S)-selective-transaminase for asymmetric synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine [PDF]
, 2016 Amine transaminases offer an environmentally sustainable synthesis route for the production of pure chiral amines. However, their catalytic efficiency toward bulky ketone substrates is greatly limited by steric hindrance and therefore presents a great ...
Allen, Christopher C.R. +12 more
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