Results 11 to 20 of about 251,409 (391)

On the flexibility of the cellular amination network in E coli

eLife, 2022
Ammonium (NH4+) is essential to generate the nitrogenous building blocks of life. It gets assimilated via the canonical biosynthetic routes to glutamate and is further distributed throughout metabolism via a network of transaminases.
Helena Schulz-Mirbach, Alexandra Müller, Tong Wu, Pascal Pfister, Selçuk Aslan, Lennart Schada von Borzyskowski, Tobias J Erb, Arren Bar-Even, Steffen N Lindner   +8 more
doaj   +1 more source

Synthesis of Sitagliptin Intermediate by a Multi-Enzymatic Cascade System Using Lipase and Transaminase With Benzylamine as an Amino Donor

Frontiers in Bioengineering and Biotechnology, 2021
Herein, we report the development of a multi-enzyme cascade using transaminase (TA), esterase, aldehyde reductase (AHR), and formate dehydrogenase (FDH), using benzylamine as an amino donor to synthesize the industrially important compound sitagliptin ...
Taresh P. Khobragade, Sharad Sarak, Amol D. Pagar, Hyunwoo Jeon, Pritam Giri, Hyungdon Yun   +5 more
doaj   +1 more source

Mechanisms of ethanol liver damage in rats with different emotionality

Journal of Education, Health and Sport, 2021
Alcoholic liver disease is associated with liver injury ranging from steatosis to steatohepatitis, fibrosis and cirrhosis. One of the mechanisms of organs damage is cytokines influences. The intensity of injury depends on individual reactivety.The aim of
O. A. Коstiuk, O. V. Denefil
doaj   +1 more source

Dual-function transaminases with hybrid nanoflower for the production of value-added chemicals from biobased levulinic acid

Frontiers in Bioengineering and Biotechnology, 2023
The U.S. Department of Energy has listed levulinic acid (LA) as one of the top 12 compounds derived from biomass. LA has gained much attention owing to its conversion into enantiopure 4-aminopentanoic acid through an amination reaction.
Taresh P. Khobragade, Pritam Giri, Amol D. Pagar, Mahesh D. Patil, Sharad Sarak, Sangwoo Joo, Younghwan Goh, Seohee Jung, Hyunseok Yoon, Subin Yun, Youkyoung Kwon, Hyungdon Yun   +11 more
doaj   +1 more source

TRANSAMINASES

Journal of Biological Chemistry, 1945
Blanco y ...
Green, David E., Leloir, Luis Federico, Nocito, V   +2 more
openaire   +2 more sources

Enzymes from Extreme Environments and their Industrial Applications

Frontiers in Bioengineering and Biotechnology, 2015
This article will discuss the importance of specific extremophilic enzymes for applications in industrial biotechnology. It will specifically address those enzymes that have applications in the area of biocatalysis.
Jennifer Ann Littlechild
doaj   +1 more source

Effect of anti-retroviral therapy on oxidative stress in hospitalized HIV-infected adults with and without TB. [PDF]

, 2018
BackgroundHIV infection and opportunistic infections cause oxidative stress (OS), which is associated with tissue damage. Anti-retroviral therapy (ART) is used to treat HIV and decrease the risk of opportunistic infections, but it is unclear whether ART ...
Andama, Alfred, Bukenya, Andrew, Byanyima, Patrick, Davis, J Lucian, Huang, Laurence, Kaswabuli, Sylvia, Matovu, Denis Kasozi, Mayanja-Kizza, Harriet, Musisi, Emmanuel, Sanyu, Ingvar, Seremba, Emmanuel, Sessolo, Abdul, Walter, Nicholas D, Worodria, William, Zawedde, Josephine   +14 more
core   +3 more sources

Biosynthesis of the Stress-Protectant and Chemical Chaperon Ectoine: Biochemistry of the Transaminase EctB

Frontiers in Microbiology, 2019
Bacteria frequently adapt to high osmolarity surroundings through the accumulation of compatible solutes. Ectoine is a prominent member of these types of stress protectants and is produced via an evolutionarily conserved biosynthetic pathway beginning ...
Alexandra A. Richter, Alexandra A. Richter, Christopher-Nils Mais, Christopher-Nils Mais, Laura Czech, Laura Czech, Kyra Geyer, Astrid Hoeppner, Sander H. J. Smits, Sander H. J. Smits, Tobias J. Erb, Tobias J. Erb, Gert Bange, Gert Bange, Erhard Bremer, Erhard Bremer   +15 more
doaj   +1 more source

Transaminases in Shigellæ [PDF]

Nature, 1959
NUMEROUS investigations have been made of the transaminase system in bacteria, and these have been reviewed by Meister1. The only reference to the transaminase activity in Shigellae appears to be the one mentioned by Lichstein and Cohen2 on a strain of Shigella dysenteriae (Shiga).
openaire   +2 more sources

Relationship between electrocardiogram and findings of serum protein, transaminase and chest CT in male AIDS patients [PDF]

Journal of Men's Health
To investigate the relationship between electrocardiogram (ECG) and findings of serum protein, transaminase and chest computed tomography (CT) in male acequired immune deficiency syndrome (AIDS) patients.
Hong Lv, Ping Du, Linyu Zeng, Ziyuan Shi, Pingping Zheng   +4 more
doaj   +1 more source