Transaminitis among Patients with Dengue Fever Visiting a Tertiary Care Centre
Introduction: Transaminitis is a condition where serum aspartate transaminase and alanine transaminase increase indicating liver dysfunction. One such disease where liver involvement might be observed is dengue, which is a mosquito-borne viral infection.
Rabindra Jang Rayamajhi+5 more
doaj +1 more source
Ramadan Fasting Model Exerts Hepatoprotective, Anti-obesity, and Anti-Hyperlipidemic Effects in an Experimentally-induced Nonalcoholic Fatty Liver in Rats [PDF]
Background: The epidemic of nonalcoholic fatty liver disease (NAFLD) and its metabolic effects present a serious public health concern. We hypothesized that the Ramadan fasting model (RFM), which involves fasting from dawn to dusk for a month, could provide potential therapeutic benefits and mitigate NAFLD.
arxiv
Prediction of liver disease in patients whose liver function tests have been checked in primary care : model development and validation using population-based observational cohorts [PDF]
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
Altman+34 more
core +4 more sources
Impact of SARS-CoV-2 infection on liver disease
Abnormal liver biochemistry is not a rare finding in the context of SARS-CoV-2 infection, regardless of patients having pre-existing chronic disease or ...
Salgüero Fernández Sergio+10 more
doaj +1 more source
Mice with low levels of Shc proteins display reduced glycolytic and increased gluconeogenic activities in liver. [PDF]
Shc proteins play a role in energy metabolism through interaction with the insulin receptor. The aim of this study was to determine whether Shc proteins influence liver glycolysis and gluconeogenesis under both fed and fasted states. Decreased glycolytic
Cortopassi, Gino A+5 more
core +3 more sources
Quantitative Methods for Optimizing Patient Outcomes in Liver Transplantation [PDF]
Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be a major problem.
arxiv
Objectives: To determine the natural history of abnormalities in liver function tests (LFTs), derive predictive algorithms for liver disease and identify the most cost-effective strategies for further investigation.
PT Donnan+6 more
doaj +1 more source
A novel technique for selective NF-kappa B inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion. [PDF]
Background and aims: The transcription factor nuclear factor kappa B (NF-kB) has risen as a promising target for anti-inflammatory therapeutics. In the liver, however, NFkB inhibition mediates both damaging and protective effects.
A. Hartkorn+11 more
core +1 more source
The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminase from Halomonas elongata (HEWT).
M. Planchestainer+5 more
semanticscholar +1 more source