Results 141 to 150 of about 50,464 (295)
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu+9 more
wiley +1 more source
Advances in the Molecular Modification of Microbial ω-Transaminases for Asymmetric Synthesis of Bulky Chiral Amines. [PDF]
Gao X+7 more
europepmc +1 more source
Cryogel‐Based Dendritic Cell Immunotherapy for Post‐Surgical Breast Cancer Treatment
A multifunctional GelMA cryogel enables dendritic cell immunotherapy that synergizes with doxorubicin and PD‐1 blockade, driving robust post‐surgical T‐cell immunity and suppressing TNBC recurrence. Abstract Triple‐negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options.
Lam‐Duc‐Huy Nguyen+7 more
wiley +1 more source
Structural insights and rational design of Pseudomonasputida KT2440 omega transaminases for enhanced biotransformation of (R)-PAC to (1R, 2S)-Norephedrine. [PDF]
Das P, Noronha S, Bhaumik P.
europepmc +1 more source
TRANSAMINASES IN SMOOTH BRUCELLA ABORTUS, STRAIN 19
Robert A. Altenbern+1 more
openalex +1 more source
Sulphasalazine and hepatic transaminases. [PDF]
Hilary A Capell, John Hunter, T Pullar
openaire +3 more sources
A Fe (III)–Pt (II) porphyrin framework‐based radiosensitizer (FPTM‐LP) is constructed to serve as an oxygen economizer, hypoxia self‐monitoring device, and reactive oxygen species (ROS) amplifier. The glutathione (GSH)/pH‐responsive release of lonidamine achieves oxygen‐economization to combat hypoxia‐induced radioresistance guided by near infrared ...
Shiye Du+9 more
wiley +1 more source
Hepatic Phenotype in NBAS-Associated Disease: Clinical Course, Prognostic Factors and Outcome in 230 Patients. [PDF]
Peters B+32 more
europepmc +1 more source